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Cytosolic purine 5'-nucleotidase

Summary

UniProt ID

P49902

Gene Symbol

NT5C2
NT5B
NT5CP
PNT5

Organism

Homo sapiens (human)

External Links

GlyGen: P49902
PubChem: P49902
The Human Metabolome Database: HMDBP03750
The O-GlcNAc Database: P49902

Annotation

Keyword

3D-structure
ATP-binding
Allosteric enzyme
Alternative splicing
Cytoplasm
Disease variant
Hereditary spastic paraplegia
Hydrolase
Magnesium
Metal-binding
Nucleotide metabolism
Phosphoprotein
Reference proteome
Transferase

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
allantoin metabolic process
GMP metabolic process
IMP catabolic process
IMP metabolic process
dGMP metabolic process
adenosine metabolic process
negative regulation of defense response to virus by host
protein K48-linked ubiquitination

Displaying **all 2** entries
GO Term
cytoplasm
cytosol

Displaying **all 9** entries
GO Term
metal ion binding
nucleoside phosphotransferase activity
IMP 5'-nucleotidase activity
GMP 5'-nucleotidase activity
identical protein binding
ATP binding
5'-nucleotidase activity
ubiquitin protein ligase activity
XMP 5'-nucleosidase activity

Annotation information from UniProt.

Sequence

MSTSWSDRLQNAADMPANMDKHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDILKSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHTHVDINEMESPLATRNRTSVDFKDTDYKRHQLTRSISEIKPPNLFPLAPQEITHCHDEDDDEEEEEEEE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites