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P2X purinoceptor 1

Summary

UniProt ID

P51575

Gene Symbol

P2RX1
P2X1

Gene ID

5023

Organism

Homo sapiens (human)

External Links

GlyGen: P51575
PubChem: P51575
The Human Metabolome Database: HMDBP07859
RaftProt: P51575
Re-Glyco: P51575

Annotation

Keyword

3D-structure
ATP-binding
Apoptosis
Cell membrane
Disulfide bond
Glycoprotein
Ligand-gated ion channel
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
glutamatergic synapse
specific granule membrane
plasma membrane
secretory granule membrane
protein-containing complex
postsynaptic membrane
external side of plasma membrane
membrane raft
presynaptic active zone membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 16 in total

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GO Term
monoatomic ion transport
apoptotic process
signal transduction
insemination
regulation of blood pressure
platelet activation
synaptic transmission, glutamatergic
regulation of presynaptic cytosolic calcium ion concentration
serotonin secretion by platelet
regulation of vascular associated smooth muscle contraction

Displaying **all 8** entries
GO Term
ligand-gated calcium channel activity
suramin binding
purinergic nucleotide receptor activity
extracellularly ATP-gated monoatomic cation channel activity
monoatomic cation channel activity
ATP binding
identical protein binding
protein-containing complex binding

Annotation information from UniProt.

Sequence

MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSGLISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEHPEGGICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLREAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESGQNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNLSPGFNFRFARHFVENGTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENMRTS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	GlyTouCan ID	Source
153	N-linked (GlcNAc...) asparagine		UniProt GlyGen
184	N-linked (GlcNAc...) asparagine		UniProt GlyGen
242	N-linked (GlcNAc...) asparagine	G86182NS G95177YH	UniProt GlyGen
300	N-linked (GlcNAc...) asparagine		UniProt GlyGen