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Glypican-3

Summary
UniProt ID
P51654
Gene Symbol
  • GPC3
  • OCI5
Organism
Homo sapiens (human)
External Links
GlycoProtDB
GPDB0011721
GlyGen
P51654
PubChem
P51654
The O-GlcNAc Database
P51654
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • GPI-anchor
  • Heparan sulfate
  • Phosphoprotein
  • Protease inhibitor
  • Pyrrolidone carboxylic acid
  • Reference proteome
  • Signal
Gene Ontology (GO)
Displaying 1 entry
GO Term
peptidyl-dipeptidase inhibitor activity
Annotation information from UniProt.
Sequence
MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 7 entries
Position Description PubMed ID GlyTouCan ID Source
124 N-linked (GlcNAc...) asparagine
241 N-linked (GlcNAc...) asparagine
359
418 N-linked (GlcNAc...) asparagine
495 O-linked (Xyl...) (glycosaminoglycan) serine
509 O-linked (Xyl...) (glycosaminoglycan) serine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 11 - 14 of 14 in total
Pathway Name Organism
RSV-host interactions Homo sapiens
Regulation of IGF Activity by IGFBP Homo sapiens
Respiratory syncytial virus (RSV) attachment and entry Homo sapiens
Retinoid metabolism and transport Homo sapiens
Disease
Displaying entries 51 - 60 of 220 in total
DO ID Disease Name Source
DOID:10966 lipoid nephrosis
DOID:11111 hydronephrosis
DOID:1115 sarcoma
DOID:11383 cryptorchidism
DOID:1148 polydactyly
DOID:11712 lipoatrophic diabetes mellitus
DOID:11832 visual epilepsy
DOID:1184 nephrotic syndrome
DOID:11984 hypertrophic cardiomyopathy
DOID:12271 aniridia
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024