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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Glypican-3
Summary
- UniProt ID
- P51654
- Gene Symbol
-
- GPC3
- OCI5
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011721
- GlyGen
- P51654
- PubChem
- P51654
- The O-GlcNAc Database
- P51654
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Direct protein sequencing
- Disease variant
- Disulfide bond
- GPI-anchor
- Heparan sulfate
- Phosphoprotein
- Protease inhibitor
- Pyrrolidone carboxylic acid
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| embryonic hindlimb morphogenesis |
| regulation of canonical Wnt signaling pathway |
| negative regulation of canonical Wnt signaling pathway |
| positive regulation of canonical Wnt signaling pathway |
| GO Term |
|---|
| endoplasmic reticulum lumen |
| Golgi lumen |
| cell surface |
| extracellular region |
| plasma membrane |
| collagen-containing extracellular matrix |
| side of membrane |
| lysosomal lumen |
| GO Term |
|---|
| peptidyl-dipeptidase inhibitor activity |
Sequence
MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQQATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 124 | N-linked (GlcNAc...) asparagine | |||
| 241 | N-linked (GlcNAc...) asparagine | |||
| 359 |
|
|||
| 418 | N-linked (GlcNAc...) asparagine |
|
||
| 495 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 509 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
|
|
G45395BF
G00912UN
G41071NU
G80920RR
G62765YT
G31852PQ
G02815KT
G37412TK
G27058EU
G57321FI
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| RSV-host interactions | Homo sapiens |
| Regulation of IGF Activity by IGFBP | Homo sapiens |
| Respiratory syncytial virus (RSV) attachment and entry | Homo sapiens |
| Retinoid metabolism and transport | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050902 | medulloblastoma | |
| DOID:0060248 | Simpson-Golabi-Behmel syndrome type 1 | |
| DOID:0060249 | scoliosis | |
| DOID:0060262 | gallbladder disease | |
| DOID:0060320 | inguinal hernia | |
| DOID:0060321 | umbilical hernia | |
| DOID:0060327 | omphalocele | |
| DOID:0060476 | Perlman syndrome | |
| DOID:0060770 | dextro-looped transposition of the great arteries | |
| DOID:0060771 | obsolete dextro-looped transposition of the great arteries 1 |
