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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
6-phosphogluconate dehydrogenase, decarboxylating
Summary
- UniProt ID
- P52209
- Gene Symbol
-
- PGD
- PGDH
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Gluconate utilization
- NADP
- Oxidoreductase
- Pentose shunt
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| pentose-phosphate shunt |
| pentose-phosphate shunt, oxidative branch |
| pentose biosynthetic process |
| D-gluconate catabolic process |
| GO Term |
|---|
| nucleus |
| extracellular exosome |
| cytosol |
| GO Term |
|---|
| phosphogluconate dehydrogenase (decarboxylating) activity |
| NADP binding |
Sequence
MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSYNA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 50 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| NFE2L2 regulates pentose phosphate pathway genes | Homo sapiens |
| Pentose phosphate pathway | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050759 | myotonic dystrophy type 2 | |
| DOID:0050778 | Meckel syndrome | |
| DOID:0050819 | obsolete Matthew-Wood syndrome | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0070117 | Meckel syndrome 3 | |
| DOID:0080348 | Alzheimer's disease 1 | |
| DOID:0080522 | thyroid gland anaplastic carcinoma | |
| DOID:0090103 | Huntington's disease-like 1 | |
| DOID:0090104 | Huntington's disease-like 2 |
