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DNA mismatch repair protein Msh6

Summary

UniProt ID

P54276

Gene Symbol

Gtmbp
Msh6

Gene ID

17688

Organism

Mus musculus (house mouse)

External Links

GlyGen: P54276
PubChem: P54276
The O-GlcNAc Database: P54276
RaftProt: P54276
Re-Glyco: P54276

Annotation

Keyword

ATP-binding
Acetylation
Chromosome
DNA repair
DNA-binding
Nucleus
Phosphoprotein
Reference proteome

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
chromatin
nucleoplasm
Golgi apparatus
cytosol
MutSalpha complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 10** entries
GO Term
intrinsic apoptotic signaling pathway in response to DNA damage
response to UV
intrinsic apoptotic signaling pathway
mismatch repair
spermatogenesis
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
isotype switching
negative regulation of DNA recombination
determination of adult lifespan

Displaying entries **1 - 10** of 16 in total

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GO Term
MutLalpha complex binding
magnesium ion binding
DNA binding
damaged DNA binding
ATP binding
enzyme binding
ADP binding
four-way junction DNA binding
mismatched DNA binding
oxidized purine DNA binding

Annotation information from UniProt.

Sequence

MSRQSTLYSFFPKSPALGDTKKAAAEASRQGAAASGASASRGGDAAWSEAEPGSRSAAVSASSPEAKDLNGGLRRASSSAQAVPPSSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIRKKGKSVRVHVQFFDDSPTRGWVSKRMLKPYTGSKSKEAQKGGHFYSSKSEILRAMQRADEALSKDTAERLQLAVCDEPSEPEEEEETEVHEAYLSDKSEEDNYNESEEEAQPSVQGPRRSSRQVKKRRVISDSESDIGGSDVEFKPDTKQEGSSDDASSGVGDSDSEDLGTFGKGAPKRKRAMVAQGGLRRKSLKKETGSAKRATPILSETKSTLSAFSAPQNSESQTHVSGGGNDSSGPTVWYHETLEWLKPEKRRDEHRRRPDHPEFNPTTLYVPEEFLNSCTPGMRKWWQLKSQNFDLVIFYKVGKFYELYHMDAVIGVSELGLIFMKGNWAHSGFPEIAFGRFSDSLVQKGYKVARVEQTETPEMMEARCRKMAHVSKFDRVVRREICRIITKGTQTYSVLDGDPSENYSRYLLSLKEKEEETSGHTRVYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQILFEKGNLSTETKTVLKGSLSSCLQEGLIPGSQFWDATKTLRTLLEGGYFTGNGDSSTVLPLVLKGMTSESDSVGLTPGEESELALSALGGIVFYLKKCLIDQELLSMANFEEYFPLDSDTVSTVKPGAVFTKASQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERLDTCHTPFGKRLLKQWLCAPLCSPSAISDRLDAVEDLMAVPDKVTEVADLLKKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKVSGLLEEVAGGFTSKTLKQVVTLQSKSPKGRFPDLTAELQRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLDKQRSRLGCKSIVYWGIGRNRYQLEIPENFATRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDTSLKDCMRRLFCNFDKNHKDWQSAVECIAVLDVLLCLANYSQGGDGPMCRPEIVLPGEDTHPFLEFKGSRHPCITKTFFGDDFIPNDILIGCEEEAEEHGKAYCVLVTGPNMGGKSTLIRQAGLLAVMAQLGCYVPAEKCRLTPVDRVFTRLGASDRIMSGESTFFVELSETASILRHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSKSVCVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFERMNQSLQLFREVCLATEKPTINGEAIHRLLALINGL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites