GlyCosmos Portal

Submissions

Mismatch repair endonuclease PMS2

Summary

UniProt ID

P54279

Gene Symbol

Pms2

Organism

Mus musculus (house mouse)

External Links

GlyGen: P54279
PubChem: P54279

Annotation

Keyword

ATP-binding
DNA repair
Endonuclease
Nucleus
Reference proteome
Tumor suppressor

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
meiotic cell cycle
positive regulation of isotype switching to IgA isotypes
positive regulation of isotype switching to IgG isotypes
DNA repair
DNA damage response
response to xenobiotic stimulus
mismatch repair

Displaying **all 3** entries
GO Term
MutLalpha complex
cytosol
nucleoplasm

Displaying **all 7** entries
GO Term
ATP hydrolysis activity
single-stranded DNA binding
endonuclease activity
ATP binding
single base insertion or deletion binding
MutSalpha complex binding
ATP-dependent DNA damage sensor activity

Annotation information from UniProt.

Sequence

MEQTEGVSTECAKAIKPIDGKSVHQICSGQVVLSLSTAVKELIENSVDAGATTIDLRLKDYGVDLIEVSDNGCGVEEENFEGLALKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHGSASVGTRLVFDHNGKITQKTPYPRPKGTTVSVQHLFYTLPVRYKEFQRNIKKEYAKMVQVLQAYCIISAGVRVSCTNQLGQGKRQPVVCTSGSSGMKENIGSVFGQKQLQSLIPFVQLPPSDAVCEEYGLSTSRTPQNLFYVSGFISQCTHGAGRSATDRQFFFINQRPCDPAKVSKLVNEVYHMYNRHQYPFVVLNVSVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDANKLNVNQQPLLDVEGNLVKLHTAELEKPVPGKQDNSPSLKSTADEKRVASISRLREAFSLHPTKEIKSRGPETAELTRSFPSEKRGVLSSYPSDVISYRGLRGSQDKLVSPTDSPGDCMDREKIEKDSGLSSTSAGSEEGFSTPEVASSFSSDYNVSSPEDRPSQETINCGDLDCRPPGTGQSLKPEDHGYQCKALPLARLSPTNAKRFKTEERPSNVNISQRLPGPQSTSAAEVDVAIKMNKRIVLLEFSLSSLAKRMKQLQHLKAQNKHELSYRKFRAKICPGENQAAEDELRKEISKSMFAEMEILGQFNLGFIVTKLKEDLFLVDQHAADEKYNFEMLQQHTVLQAQRLITPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDEDAPVTERAKLISLPTSKNWTFGPQDIDELIFMLSDSPGVMCRPSRVRQMFASRACRKSVMIGTALNASEMKKLITHMGEMDHPWNCPHGRPTMRHVANLDVISQN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites