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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pancreatic secretory granule membrane major glycoprotein GP2
Summary
- UniProt ID
- P55259
- Gene Symbol
-
- GP2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cytoplasmic vesicle
- Disulfide bond
- EGF-like domain
- Endosome
- GPI-anchor
- Innate immunity
- Receptor
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| neutrophil migration |
| antigen transcytosis by M cells in mucosal-associated lymphoid tissue |
| innate immune response |
| GO Term |
|---|
| antigen binding |
Sequence
MPHLMERMVGSGLLWLALVSCILTQASAVQRGYGNPIEASSYGLDLDCGAPGTPEAHVCFDPCQNYTLLDEPFRSTENSAGSQGCDKNMSGWYRFVGEGGVRMSETCVQVHRCQTDAPMWLNGTHPALGDGITNHTACAHWSGNCCFWKTEVLVKACPGGYHVYRLEGTPWCNLRYCTVPRDPSTVEDKCEKACRPEEECLALNSTWGCFCRQDLNSSDVHSLQPQLDCGPREIKVKVDKCLLGGLGLGEEVIAYLRDPNCSSILQTEERNWVSVTSPVQASACRNILERNQTHAIYKNTLSLVNDFIIRDTILNINFQCAYPLDMKVSLQAALQPIVSSLNVSVDGNGEFIVRMALFQDQNYTNPYEGDAVELSVESVLYVGAILEQGDTSRFNLVLRNCYATPTEDKADLVKYFIIRNSCSNQRDSTIHVEENGQSSESRFSVQMFMFAGHYDLVFLHCEIHLCDSLNEQCQPSCSRSQVRSEVPAIDLARVLDLGPITRRGAQSPGVMNGTPSTAGFLVAWPMVLLTVLLAWLF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 65 | N-linked (GlcNAc...) (high mannose) asparagine |
|
||
| 88 | N-linked (GlcNAc...) asparagine | |||
| 122 | N-linked (GlcNAc...) asparagine |
|
||
| 134 | N-linked (GlcNAc...) asparagine |
|
||
| 204 | N-linked (GlcNAc...) asparagine |
|
||
| 216 | N-linked (GlcNAc...) asparagine |
|
||
| 260 | N-linked (GlcNAc...) asparagine | |||
| 291 | N-linked (GlcNAc...) asparagine | |||
| 342 | N-linked (GlcNAc...) asparagine |
|
||
| 362 | N-linked (GlcNAc...) asparagine |
|
G62765YT
G11314AS
G36379GD
G57317CE
G20210JR
G23294PN
G05724UK
G06110VR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Post-translational modification: synthesis of GPI-anchored proteins | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050819 | obsolete Matthew-Wood syndrome | |
| DOID:0060192 | Crohn's colitis | |
| DOID:0060262 | gallbladder disease | |
| DOID:0110892 | inflammatory bowel disease 1 | |
| DOID:0111459 | classic galactosemia | |
| DOID:10629 | microphthalmia | |
| DOID:14695 | galactokinase deficiency | |
| DOID:1793 | pancreatic cancer | |
| DOID:1883 | hepatitis C |
