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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Transmembrane protease serine 3
Summary
- UniProt ID
- P57727
- Gene Symbol
-
- TMPRSS3
- ECHOS1
- TADG12
- Organism
- Homo sapiens (human)
External Links
Annotation
- Keyword
-
- Alternative splicing
- Autocatalytic cleavage
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Non-syndromic deafness
- Reference proteome
- Serine protease
- Signal-anchor
- Transmembrane helix
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| proteolysis |
| intracellular sodium ion homeostasis |
| sensory perception of sound |
| GO Term |
|---|
| membrane |
| neuronal cell body |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| GO Term |
|---|
| sodium channel regulator activity |
| serine-type endopeptidase activity |
Sequence
MGENDPPAVEAPFSFRSLFGLDDLKISPVAPDADAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAVLQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVSSDNLRVSSLEGQFREEFVSIDHLLPDDKVTALHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMERDLKT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 221 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
