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Sestrin-2

Summary

UniProt ID

P58004

Gene Symbol

Hi95
SESN2
SEST2

Gene ID

83667

Organism

Homo sapiens (human)

External Links

GlyGen: P58004
The O-GlcNAc Database: P58004
Re-Glyco: P58004

Annotation

Keyword

3D-structure
Acetylation
Cytoplasm
Isopeptide bond
Oxidoreductase
Phosphoprotein
Reference proteome
Ubl conjugation

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
nucleus
cytoplasm
mitochondrion
cytosol
lysosomal membrane
nucleotide-activated protein kinase complex
TORC2 complex
Atg1/ULK1 kinase complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 28 in total

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GO Term
regulation of gluconeogenesis
negative regulation of cell growth
mitochondrial DNA metabolic process
glucose homeostasis
glucose import
reactive oxygen species metabolic process
DNA damage response, signal transduction by p53 class mediator
regulation of TORC1 signaling
positive regulation of lipophagy
regulation of protein phosphorylation

Displaying **all 8** entries
GO Term
sulfiredoxin activity
GDP-dissociation inhibitor activity
leucine binding
peroxidase activity
PH domain binding
protein-containing complex binding
protein sequestering activity
oxidoreductase activity, acting on peroxide as acceptor

Annotation information from UniProt.

Sequence

MIVADSECRAELKDYLRFAPGGVGDSGPGEEQRESRARRGPRGPSAFIPVEEVLREGAESLEQHLGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHYLLLHTDGPLASSWRHYIAIMAAARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLSEINKLLAHRPWLITKEHIQALLKTGEHTWSLAELIQALVLLTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSPPSRDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEEMESRFELEKSESLLVTPSADILEPSPHPDMLCFVEDPTFGYEDFTRRGAQAPPTFRAQDYTWEDHGYSLIQRLYPEGGQLLDEKFQAAYSLTYNTIAMHSGVDTSVLRRAIWNYIHCVFGIRYDDYDYGEVNQLLERNLKVYIKTVACYPEKTTRRMYNLFWRHFRHSEKVHVNLLLLEARMQAALLYALRAITRYMT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites