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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Toll/interleukin-1 receptor domain-containing adapter protein
Summary
- UniProt ID
- P58753
- Gene Symbol
-
- TIRAP
- MAL
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cytoplasm
- Disulfide bond
- Inflammatory response
- Innate immunity
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cellular response to bacterial lipopeptide |
| cellular response to lipoteichoic acid |
| positive regulation of chemokine (C-X-C motif) ligand 2 production |
| GO Term |
|---|
| cytoplasm |
| plasma membrane |
| endocytic vesicle |
| cytosol |
| cell surface |
| extrinsic component of cytoplasmic side of plasma membrane |
| ruffle membrane |
Sequence
MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLSGLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMRYLQTLS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ER-Phagosome pathway | Homo sapiens |
| IRAK4 deficiency (TLR2/4) | Homo sapiens |
| MyD88 deficiency (TLR2/4) | Homo sapiens |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | Homo sapiens |
