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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Eukaryotic initiation factor 4A-I
Summary
- UniProt ID
- P60843
- Gene Symbol
-
- Eif4a1
- Ddx2a
- Eif4a
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Helicase
- Initiation factor
- Isopeptide bond
- Phosphoprotein
- RNA-binding
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasmic translational initiation |
| translational initiation |
| GO Term |
|---|
| eukaryotic translation initiation factor 4F complex |
| cytosol |
| GO Term |
|---|
| ATP hydrolysis activity |
| RNA helicase activity |
| double-stranded RNA binding |
| translation initiation factor activity |
| ATP binding |
Sequence
MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | Mus musculus |
| Deadenylation of mRNA | Mus musculus |
| GTP hydrolysis and joining of the 60S ribosomal subunit | Mus musculus |
| ISG15 antiviral mechanism | Mus musculus |
| L13a-mediated translational silencing of Ceruloplasmin expression | Mus musculus |
| Ribosomal scanning and start codon recognition | Mus musculus |
| Translation initiation complex formation | Mus musculus |
