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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
NEDD8-conjugating enzyme Ubc12
Summary
- UniProt ID
- P61081
- Gene Symbol
-
- UBE2M
- UBC12
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P61081
- PubChem
- P61081
- The Human Metabolome Database
- HMDBP00563
- The O-GlcNAc Database
- P61081
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Methylation
- Phosphoprotein
- Reference proteome
- Transferase
- Ubl conjugation pathway
- Gene Ontology (GO)
| GO Term |
|---|
| post-translational protein modification |
| protein neddylation |
| protein modification process |
| positive regulation of neuron apoptotic process |
| GO Term |
|---|
| cytosol |
| nucleoplasm |
| nucleus |
| GO Term |
|---|
| ubiquitin-protein transferase activity |
| ATP binding |
| NEDD8 conjugating enzyme activity |
| NEDD8 transferase activity |
Sequence
MIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNFKLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFERCLK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Antigen processing: Ubiquitination & Proteasome degradation | Homo sapiens |
| Dectin-1 mediated noncanonical NF-kB signaling | Homo sapiens |
| NIK-->noncanonical NF-kB signaling | Homo sapiens |
| Neddylation | Homo sapiens |
| TGF-beta receptor signaling activates SMADs | Homo sapiens |
