GlyCosmos Portal

Submissions

Transforming growth factor beta-2 proprotein

Summary

UniProt ID

P61812

Gene Symbol

TGFB2

Organism

Homo sapiens (human)

External Links

GlyConnect

1836

GlyGen

P61812

PubChem

P61812

The Human Metabolome Database

HMDBP14497

The O-GlcNAc Database

P61812

O-GlcNAcAtlas

P61812

Annotation

Keyword

3D-structure
Alternative splicing
Aortic aneurysm
Chromosomal rearrangement
Cleavage on pair of basic residues
Direct protein sequencing
Disease variant
Disulfide bond
Extracellular matrix
Glycoprotein
Growth factor
Mitogen
Reference proteome
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 91 in total

1

2

3

4

5

…

Next ›

Last »
GO Term
male gonad development
cardioblast differentiation
positive regulation of epithelial cell migration
positive regulation of epithelial to mesenchymal transition
negative regulation of macrophage cytokine production
collagen fibril organization
embryonic limb morphogenesis
response to progesterone
positive regulation of stress-activated MAPK cascade
regulation of transforming growth factor beta2 production

Displaying **all 6** entries
GO Term
extracellular region
extracellular space
axon
neuronal cell body
collagen-containing extracellular matrix
platelet alpha granule lumen

Displaying **all 8** entries
GO Term
growth factor activity
type III transforming growth factor beta receptor binding
protein homodimerization activity
signaling receptor binding
amyloid-beta binding
type II transforming growth factor beta receptor binding
cytokine activity
transforming growth factor beta receptor binding

Annotation information from UniProt.

Sequence

MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPEEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSENAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFRVFRLQNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYRLESQQTNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	GlyTouCan ID	Source
72	N-linked (GlcNAc...) asparagine	G02815KT	UniProt GlyGen
140	N-linked (GlcNAc...) asparagine	G80920RR G62765YT G41247ZX G02815KT G06110VR	UniProt GlyGen GlyConnect
230		G49108TO	GlyGen The O-GlcNAc Database
241	N-linked (GlcNAc...) asparagine	G83460ZZ	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
ECM proteoglycans	Homo sapiens
Molecules associated with elastic fibres	Homo sapiens
Platelet degranulation	Homo sapiens
TGF-beta receptor signaling activates SMADs	Homo sapiens
TGFBR3 regulates TGF-beta signaling	Homo sapiens