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26S proteasome regulatory subunit 8

Summary

UniProt ID

P62196

Gene Symbol

Psmc5
Sug1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P62196
PubChem: P62196
RaftProt: P62196
O-GlcNAcAtlas: P62196

Annotation

Keyword

ATP-binding
Acetylation
Cytoplasm
Nucleus
Phosphoprotein
Proteasome
Reference proteome

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
regulation of transcription by RNA polymerase II
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of DNA-templated transcription
modulation of chemical synaptic transmission
positive regulation of inclusion body assembly

Displaying entries **1 - 10** of 12 in total

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GO Term
postsynapse
nucleus
cytoplasm
inclusion body
cytoplasmic vesicle
proteasome regulatory particle, base subcomplex
proteasome accessory complex
cytosolic proteasome complex
transcription factor TFIIH holo complex
nuclear proteasome complex

Displaying **all 8** entries
GO Term
ATP binding
ATP hydrolysis activity
proteasome-activating activity
DNA-binding transcription factor binding
general transcription initiation factor binding
signaling receptor binding
TBP-class protein binding
thyrotropin-releasing hormone receptor binding

Annotation information from UniProt.

Sequence

MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
272			G49108TO	GlyGen
337			G80920RR	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **21 - 30** of 49 in total

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Pathway Name	Organism
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	Mus musculus
FCERI mediated NF-kB activation	Mus musculus
G2/M Checkpoints	Mus musculus
GLI3 is processed to GLI3R by the proteasome	Mus musculus
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	Mus musculus
Hedgehog 'on' state	Mus musculus
Hedgehog ligand biogenesis	Mus musculus
Interleukin-1 signaling	Mus musculus
KEAP1-NFE2L2 pathway	Mus musculus
MAPK6/MAPK4 signaling	Mus musculus