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Histone deacetylase 2

Summary

UniProt ID

P70288

Gene Symbol

Hdac2
Yy1bp

Organism

Mus musculus (house mouse)

External Links

GlyGen: P70288
PubChem: P70288
The O-GlcNAc Database: P70288

Annotation

Keyword

Acetylation
Biological rhythms
Calcium
Chromatin regulator
Cytoplasm
Hydrolase
Isopeptide bond
Metal-binding
Nucleus
Phosphoprotein
Reference proteome
Repressor
S-nitrosylation
Transcription regulation
Ubl conjugation
Zinc

Gene Ontology (GO)

Displaying entries **31 - 40** of 46 in total

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GO Term
chromatin remodeling
protein deacetylation
regulation of cell fate specification
circadian regulation of gene expression
chromatin organization
positive regulation of cell population proliferation
epidermal cell differentiation
neuron differentiation
cellular response to trichostatin A
positive regulation of tyrosine phosphorylation of STAT protein

Displaying entries **1 - 10** of 12 in total

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GO Term
NuRD complex
transcription repressor complex
RNA polymerase II transcription repressor complex
histone deacetylase complex
nucleoplasm
transcription regulator complex
replication fork
chromatin
heterochromatin
nucleus

Displaying entries **1 - 10** of 16 in total

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GO Term
metal ion binding
DNA-binding transcription factor binding
promoter-specific chromatin binding
heat shock protein binding
chromatin DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
transcription corepressor binding
histone deacetylase activity
deacetylase activity
protein lysine deacetylase activity

Annotation information from UniProt.

Sequence

MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVAKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDPKGAKSEQLSNP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
276			G53434XO	GlyGen
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
Factors involved in megakaryocyte development and platelet production	Mus musculus
HDACs deacetylate histones	Mus musculus
Notch-HLH transcription pathway	Mus musculus
RNA Polymerase I Transcription Initiation	Mus musculus
Regulation of MECP2 expression and activity	Mus musculus
Regulation of PTEN gene transcription	Mus musculus
Regulation of TP53 Activity through Acetylation	Mus musculus
STAT3 nuclear events downstream of ALK signaling	Mus musculus
SUMOylation of chromatin organization proteins	Mus musculus