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Natural resistance-associated macrophage protein 1

Summary

UniProt ID

P70553

Gene Symbol

Slc11a1
Bcg
Nramp1

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P70553

Annotation

Keyword

Endosome
Glycoprotein
Iron transport
Lysosome
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 35 in total

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GO Term
negative regulation of cytokine production
positive regulation of cytokine production
T cell proliferation involved in immune response
positive regulation of dendritic cell antigen processing and presentation
positive regulation of T-helper 1 type immune response
iron ion transport
intracellular iron ion homeostasis
phagocytosis
inflammatory response
response to bacterium

Displaying **all 8** entries
GO Term
lysosome
lysosomal membrane
plasma membrane
tertiary granule membrane
phagocytic vesicle membrane
late endosome membrane
endosome membrane
late endosome

Displaying **all 6** entries
GO Term
transition metal ion transmembrane transporter activity
metal cation:proton antiporter activity
protein homodimerization activity
manganese ion transmembrane transporter activity
cadmium ion transmembrane transporter activity
iron ion transmembrane transporter activity

Annotation information from UniProt.

Sequence

MIRDKNPQRVNRPSYGSISSLPSPAPQPEPSRNTYLSEKIPIPSTEQLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEICHLYYPKVPRILLWLTIELAIVGSDMQEVIGTAISFNLLSAGRIPLWGGVLITIVDTFFFLFLDNYGLRKLEAFFGFLVTIMALTFGYEYVVARPSQGALLKGLFLPSCPGCGQPELLQAVGIVGAIIMPHNIYLHSALVKSREVDRTRRGDVREANMYFLTEATIALFVSFIINLFVMAVFGQAFYQQTNEEAFNICANSSLHNYAKIFPRDNNTVSVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTMTGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPAVMQEFANGWLSKVITSCIMALVCAINLYFVISYLPSLPHPAYFGLVALLAIGYLGLTAYLAWTCCIAHGAKFLTHSSHQRFLYGLPIEEQEGREGSG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
280	N-linked (GlcNAc...) asparagine			UniProt
294	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Ion influx/efflux at host-pathogen interface	Rattus norvegicus
Metal ion SLC transporters	Rattus norvegicus
Neutrophil degranulation	Rattus norvegicus
ROS and RNS production in phagocytes	Rattus norvegicus