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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Glypican-5
Summary
- UniProt ID
- P78333
- Gene Symbol
-
- GPC5
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Cell membrane
- GPI-anchor
- Heparan sulfate
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of canonical Wnt signaling pathway |
| cell migration |
| regulation of protein localization to membrane |
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| membrane |
| collagen-containing extracellular matrix |
| Golgi lumen |
| cell surface |
| side of membrane |
| lysosomal lumen |
Sequence
MDAQTWPVGFRCLLLLALVGSARSEGVQTCEEVRKLFQWRLLGAVRGLPDSPRAGPDLQVCISKKPTCCTRKMEERYQIAARQDMQQFLQTSSSTLKFLISRNAAAFQETLETLIKQAENYTSILFCSTYRNMALEAAASVQEFFTDVGLYLFGADVNPEEFVNRFFDSLFPLVYNHLINPGVTDSSLEYSECIRMARRDVSPFGNIPQRVMGQMGRSLLPSRTFLQALNLGIEVINTTDYLHFSKECSRALLKMQYCPHCQGLALTKPCMGYCLNVMRGCLAHMAELNPHWHAYIRSLEELSDAMHGTYDIGHVLLNFHLLVNDAVLQAHLNGQKLLEQVNRICGRPVRTPTQSPRCSFDQSKEKHGMKTTTRNSEETLANRRKEFINSLRLYRSFYGGLADQLCANELAAADGLPCWNGEDIVKSYTQRVVGNGIKAQSGNPEVKVKGIDPVINQIIDKLKHVVQLLQGRSPKPDKWELLQLGSGGGMVEQVSGDCDDEDGCGGSGSGEVKRTLKITDWMPDDMNFSDVKQIHQTDTGSTLDTTGAGCAVATESMTFTLISVVMLLPGIW
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 120 | N-linked (GlcNAc...) asparagine |
|
||
| 237 | N-linked (GlcNAc...) asparagine |
|
||
| 379 |
|
|||
| 441 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 486 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 495 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 507 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 509 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 527 | N-linked (GlcNAc...) asparagine |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Release of Hh-Np from the secreting cell | Homo sapiens |
| Respiratory syncytial virus (RSV) attachment and entry | Homo sapiens |
| Retinoid metabolism and transport | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110250 | cataract 16 multiple types | |
| DOID:0110251 | cataract 15 multiple types | |
| DOID:0110252 | cataract 37 | |
| DOID:0110253 | cataract 14 multiple types | |
| DOID:0110254 | cataract 25 | |
| DOID:0110255 | cataract 5 multiple types | |
| DOID:0110256 | cataract 21 multiple types | |
| DOID:0110257 | cataract 24 | |
| DOID:0110258 | cataract 10 multiple types | |
| DOID:0110259 | cataract 43 |
