Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
Disintegrin and metalloproteinase domain-containing protein 17

Summary
UniProt ID
P78536
Gene Symbol
  • ADAM17
  • CSVP
  • TACE
Organism
Homo sapiens (human)
External Links
GlycoProtDB
GPDB0011762
GlyConnect
GlyGen
P78536
PubChem
P78536
The O-GlcNAc Database
P78536
O-GlcNAcAtlas
P78536
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Cleavage on pair of basic residues
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Metal-binding
  • Metalloprotease
  • Notch signaling pathway
  • Phosphoprotein
  • Reference proteome
  • SH3-binding
  • Signal
  • Transmembrane helix
  • Zinc
  • Zymogen
Gene Ontology (GO)
Annotation information from UniProt.
Sequence
MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 11 - 13 of 13 in total
Position Description PubMed ID GlyTouCan ID Source
551 N-linked (GlcNAc...) asparagine
594 N-linked (GlcNAc...) asparagine
598
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 1 - 10 of 13 in total
Pathway Name Organism
Activated NOTCH1 Transmits Signal to the Nucleus Homo sapiens
CD163 mediating an anti-inflammatory response Homo sapiens
Collagen degradation Homo sapiens
Constitutive Signaling by NOTCH1 HD Domain Mutants Homo sapiens
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Homo sapiens
Constitutive Signaling by NOTCH1 PEST Domain Mutants Homo sapiens
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Homo sapiens
Growth hormone receptor signaling Homo sapiens
Nuclear signaling by ERBB4 Homo sapiens
Regulated proteolysis of p75NTR Homo sapiens
About Release Notes Help Feedback
International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.0.0

Last updated: August 19, 2024