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MIRAGE
DNA replication licensing factor MCM2
Summary
- UniProt ID
- P97310
- Gene Symbol
-
- Bm28
- Cdcl1
- Kiaa0030
- Mcm2
- Mcmd2
- Gene ID
- 17216
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Cell cycle
- Chromosome
- DNA replication
- DNA-binding
- Direct protein sequencing
- Helicase
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| chromatin |
| nucleus |
| cytoplasm |
| MCM complex |
| CMG complex |
| nuclear origin of replication recognition complex |
| GO Term |
|---|
| metal ion binding |
| helicase activity |
| ATP binding |
| ATP hydrolysis activity |
| enzyme binding |
| histone binding |
| DNA replication origin binding |
Sequence
MAESSESLSASSPARQRRRISDPLTSSPGRSSRRADALTSSPGRDLPPFEDESEGLLGTEGPMEEEEDGEELIGDGMERDYRPIPELDVYEAEGLALDDEDVEELTASQREAAERTMRQRDREAGRGLGRMRRGLLYDSSEEDEERPARKRRHVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCSKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEINMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATIILANHVAKKDNKVAVGELTDEDVKMITGLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDVLCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKKDEGLTNGGTLEPAMPNTYGVEPLPQEVLKKYIIYAKERVRPKLNQMDQDKVARMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVMEDDVNMAIRVMMESFIDTQKFSVMRSMRKTFARYLSFRRDNNDLLLFILKQLVAEQVTYQRNRFGAQQDTIEIPEKDLMDKARQINIHNLSAFYDSDLFKFNKFSRDLKRKLILQQF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 108 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of ATR in response to replication stress | Mus musculus |
| Activation of the pre-replicative complex | Mus musculus |
| Assembly of the pre-replicative complex | Mus musculus |
| Orc1 removal from chromatin | Mus musculus |
| Switching of origins to a post-replicative state | Mus musculus |
