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Adenylate cyclase type 8

Summary

UniProt ID

P97490

Gene Symbol

Adcy8

Organism

Mus musculus (house mouse)

External Links

PubChem: P97490

Annotation

Keyword

ATP-binding
Cell membrane
Cell projection
Coated pit
Cytoplasmic vesicle
Glycoprotein
Lyase
Magnesium
Manganese
Metal-binding
Methylation
Phosphoprotein
Reference proteome
Repeat
Synapse
Transmembrane helix
cAMP biosynthesis

Gene Ontology (GO)

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GO Term
memory
locomotory behavior
positive regulation of insulin secretion
glucose homeostasis
modulation of chemical synaptic transmission
regulation of cellular response to stress
glucose mediated signaling pathway
positive regulation of synaptic plasticity
positive regulation of CREB transcription factor activity
G protein-coupled opioid receptor signaling pathway

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GO Term
basolateral plasma membrane
apical plasma membrane
plasma membrane
postsynaptic density
clathrin-coated vesicle membrane
presynaptic membrane
plasma membrane raft
presynaptic active zone
excitatory synapse
Schaffer collateral - CA1 synapse

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GO Term
calcium- and calmodulin-responsive adenylate cyclase activity
actin binding
adenylate cyclase activity
calmodulin binding
ATP binding
metal ion binding
protein homodimerization activity
protein heterodimerization activity
protein dimerization activity
phosphatase binding

Annotation information from UniProt.

Sequence

MELSDVHCLSGSEELYTIQPTPPAGDDGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGGGVSRKASNPAGSGPNHHAPQLSSDSVLPLYSLGPGERAHNTGGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDNTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVTLQVLIPRLAVFSINQVLAQVVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRRDHAHCCVEMGLSMIKTIRFVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLCLPEDIVKESVSCSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRLMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAVLNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLSYDNLNHSGEDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENSNSGIIKSHYNRRTLLTPSGPEPGAQAEGTDKSDLP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
815	N-linked (GlcNAc...) asparagine	UniProt
819	N-linked (GlcNAc...) asparagine	UniProt
886	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Adenylate cyclase activating pathway	Mus musculus
Adenylate cyclase inhibitory pathway	Mus musculus
G alpha (z) signalling events	Mus musculus
Hedgehog 'off' state	Mus musculus
PKA activation	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements