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GDNF family receptor alpha-1

Summary

UniProt ID: P97785
Gene Symbol: Gfra1 Gdnfra Trnr1
Gene ID: 14585
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003816
PubChem: P97785
Re-Glyco: P97785

Annotation

Keyword: Alternative splicing Cell membrane Disulfide bond Endosome GPI-anchor Golgi apparatus Receptor Reference proteome Repeat Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	Reference
kidney development	IEA	GO_REF
cell surface receptor protein tyrosine kinase signaling pathway	ISO	GO_REF
cell surface receptor protein tyrosine kinase signaling pathway	TAS	PMID
cell surface receptor protein tyrosine kinase signaling pathway	IEA	GO_REF
nervous system development	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

glial cell-derived neurotrophic factor receptor signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

anatomical structure morphogenesis

anatomical structure development [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

system development [inference]

nervous system development

animal gross anatomical part developmental process [inference]

nervous system development

animal organ development [inference]

kidney development

gonad development [inference]

male gonad development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

glial cell-derived neurotrophic factor receptor signaling pathway

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GO Term	Evidence Code	Reference
obsolete extracellular space
multivesicular body	IEA	GO_REF
Golgi apparatus	IEA	GO_REF
plasma membrane	ISS	GO_REF
plasma membrane	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

membrane protein complex [inference]

plasma membrane protein complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

extrinsic component of membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

cell body [inference]

neuronal cell body

side of membrane [inference]

external side of plasma membrane

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GO Term	Evidence Code	Reference
neurotrophin receptor activity	ISO	GO_REF
neurotrophin receptor activity	IEA	GO_REF
integrin binding	ISO	GO_REF
integrin binding	IEA	GO_REF
glial cell-derived neurotrophic factor receptor activity	ISS	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

integrin binding

protein-containing complex binding [inference]

integrin binding

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

glial cell-derived neurotrophic factor receptor activity

neurotrophin receptor activity

immune receptor activity [inference]

cytokine receptor activity [inference]

glial cell-derived neurotrophic factor receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MFLATLYFVLPLLDLLMSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLTSGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSPYEPVNSRLSDIFRAVPFISDVFQQVEHISKGNNCLDAAKACNLDDTCKKYRSAYITPCTTSMSNEVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDVACTERRRQTIVPVCSYEERERPNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSNCLKENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEDCLKFLNFFKDNTCLKNAIQAFGNGSDVTMWQPAPPVQTTTATTTTAFRIKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGSTHLCLSDNDYGKDGLAGASSHITTKSMAAPPSCGLSSLPVMVFTALAALLSVSLAETS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
59	N-linked (GlcNAc...) asparagine	UniProt
347	N-linked (GlcNAc...) asparagine	UniProt
406	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
RAF/MAP kinase cascade	Mus musculus
RET signaling	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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