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Tyrosine-protein phosphatase non-receptor type substrate 1

Summary

UniProt ID

P97797

Gene Symbol

Bit
Myd1
Ptpns1
Shps1
Sirp
Sirpa

Gene ID

19261

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003822

GlyConnect

Tyrosine-protein phosphatase non-receptor type substrate 1

GlyGen

P97797

PubChem

P97797

The O-GlcNAc Database

P97797

RaftProt

P97797

O-GlcNAcAtlas

P97797

Re-Glyco

P97797

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Reference proteome
Repeat
SH3-binding
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying 1 entry
GO Term
plasma membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 21 in total

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GO Term
cell motility
negative regulation of phagocytosis
positive regulation of phagocytosis
actin filament organization
negative regulation of macrophage inflammatory protein 1 alpha production
negative regulation of chemokine (C-C motif) ligand 5 production
cell-matrix adhesion
negative regulation of lipopolysaccharide-mediated signaling pathway
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production

Displaying **all 4** entries
GO Term
protein phosphatase inhibitor activity
protein phosphorylated amino acid binding
SH3 domain binding
protein phosphatase binding

Annotation information from UniProt.

Sequence

MEPAGPAPGRLGPLLLCLLLSASCFCTGATGKELKVTQPEKSVSVAAGDSTVLNCTLTSLLPVGPIRWYRGVGPSRLLIYSFAGEYVPRIRNVSDTTKRNNMDFSIRISNVTPADAGIYYCVKFQKGSSEPDTEIQSGGGTEVYVLAKPSPPEVSGPADRGIPDQKVNFTCKSHGFSPRNITLKWFKDGQELHPLETTVNPSGKNVSYNISSTVRVVLNSMDVNSKVICEVAHITLDRSPLRGIANLSNFIRVSPTVKVTQQSPTSMNQVNLTCRAERFYPEDLQLIWLENGNVSRNDTPKNLTKNTDGTYNYTSLFLVNSSAHREDVVFTCQVKHDQQPAITRNHTVLGFAHSSDQGSMQTFPDNNATHNWNVFIGVGVACALLVVLLMAALYLLRIKQKKAKGSTSSTRLHEPEKNAREITQVQSLIQDTNDINDITYADLNLPKEKKPAPRAPEPNNHTEYASIETGKVPRPEDTLTYADLDMVHLSRAQPAPKPEPSFSEYASVQVQRK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 22 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
54	N-linked (GlcNAc...) asparagine		G23863VK G50045TK G02815KT G06110VR G66538GV	UniProt GlyGen GlyConnect
92	N-linked (GlcNAc...) asparagine		G80223IX G10773YW G46902YN G65092SV G23863VK G84820NF G50045TK G82119TF G05724UK G33609NS G39188ZX G25637MV G23453IV G02815KT G06110VR G00406II G60145BJ G66538GV G74724QE G14669DU G63628AV G32550BI G71838YU	UniProt GlyGen GlyConnect
110			G80223IX G23863VK G45504EY G50045TK G82119TF G94854LT G06110VR G66538GV G74724QE G14669DU G63628AV G32550BI G89753LT	GlyGen GlyConnect
112				GlyGen
168	N-linked (GlcNAc...) asparagine		G46902YN G84820NF G50045TK G72735IY G33609NS G39188ZX G23453IV G57776ZU G06110VR G66538GV G14669DU G63628AV G71838YU	GlycoProtDB UniProt GlyGen GlyConnect
170			G49108TO	The O-GlcNAc Database
180	N-linked (GlcNAc...) asparagine		G07755XJ	UniProt GlyGen
205	N-linked (GlcNAc...) asparagine		G63980BQ G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
209	N-linked (GlcNAc...) asparagine		G25541YH G57292HF G76329HL	GlycoProtDB UniProt GlyGen GlyConnect
246	N-linked (GlcNAc...) asparagine	16944957	G50045TK G72735IY G05724UK G31852PQ G33609NS G39188ZX G06110VR G66538GV G14669DU G63628AV G32550BI	GlycoProtDB UniProt GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Cell surface interactions at the vascular wall	Mus musculus
Neutrophil degranulation	Mus musculus
Signal regulatory protein family interactions	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements