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Complement C3

Summary

UniProt ID: P98094
Gene Symbol: C3
Gene ID
Organism: Eptatretus burgeri (inshore hagfish)

External Links

PubChem: P98094
Re-Glyco: P98094

Annotation

Keyword: Complement pathway Direct protein sequencing Disulfide bond Glycoprotein Inflammatory response Reference proteome Secreted Thioester bond

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
complement activation, lectin pathway	ISS	GO_REF
inflammatory response
complement activation, alternative pathway	ISS	GO_REF
complement activation, classical pathway	ISS	GO_REF
opsonization	ISS	GO_REF

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

complement activation [inference]

opsonization

activation of immune response [inference]

complement activation [inference]

immune response [inference]

humoral immune response [inference]

complement activation [inference]

innate immune response [inference]

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

immune response [inference]

humoral immune response [inference]

complement activation [inference]

innate immune response [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

regulation of immune response [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

regulation of immune response [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

Displaying **all 4** entries
GO Term	Evidence Code	Reference
classical-complement-pathway C3/C5 convertase complex	ISS	GO_REF
cell surface	ISS	GO_REF
cell surface	IEA	GO_REF
symbiont cell surface	ISS	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

extracellular protein-containing complex [inference]

classical-complement-pathway C3/C5 convertase complex

catalytic complex [inference]

classical-complement-pathway C3/C5 convertase complex

cellular anatomical structure [inference]

cell surface

other organism part [inference]

symbiont cell surface

Displaying **all 2** entries
GO Term	Evidence Code	Reference
antigen binding	ISS	GO_REF
endopeptidase inhibitor activity	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

antigen binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

VLVIAPAATSSYDDLAVAILMVDQKKITEVHVLLVNPHTGATLDEKKVKLQWDNKFIAFTKLQVTPKEVEKWKEDFVRLMVKWDGGQHMEIDIPLTSRRGLVFAQTDQPIYTPNNDVNIRLFPVTRQLNPILSSLVVDIMNPDGVVVDRIEKNAFEVEKVMELRPFHVPAITSLGDWKIVSWMKDKPQFNYTSGFKVEEYVLPTFDVSITSEQPYLHVYDKAFTIHIKAMHIYGKPVMGRAYVRYGVKHQSKRTLLSTSSALARFEQGEAMHTLRQKHILEQYPDPKLLLGQSLYVEASVISSDAGEIENSILDDIPIVASPYSIKSKWTVPFFKPGVPYIYKVLVLNPDGSPASGVPIKVSFSFDSSGNWITQKRKTMDNGIAMQTINTARNSKKLNIKVQTEDERLEQSQQAEASFTIASYSSPSGSFIHLNAHREVKSPGEHIVFDVFIKSAAKDHVLHFNYLMISNGKIHNFLQEGRKGDTTSVSLLLTPELVPQFRLVAFFILPSGELVADSIIIDVKDSCHAKLSLDVAGGKRLFSPRDNVNFDLSGESDSWVAVGVVDKAAYVLDKKNKLTANKVYKAMEASDLGCSVGSGKTGPLVFRDAGLAIMAKEISGMDDVKDPGCPNGHTRRKRELVLEIAIEKASTYPAELRKCCRDAAIESPLRLSCEERTKHIHDEGEGCQETFLECCKHVEEELLIAMEEEDEDLGRSQGEDFMIQESQVVIRSHFPESFMWEIIKLSRSAENGKSRITKKMPDSITTWDIQAVEVSQSKGLCVGPSLELTVFKQFFLKVHTPYALKQYEQVELRVVIYNYMNQDVKGEIQVKCGDGICTDAEQNEPLKSRFAVEKNSATSFSFMVVPLSSSDSSVSVLARVFGSDVHDAVEKDLRVMPEGNYEEMSRSWSVQPRRHGGQQVIVVDNETPQNVVPGTEMSAFLSAQGNLVAETIQNTLKGSKISNLLRLPRGCGEQNMMYTSITVMVARYLNRSDQWNKMGDPQLKKRSFDFITSGFASQLTYRKPDYSYAAWLHRASSTWLTAFVAKVFSQARQLVFIPVSEICGSVRWLMRKQDKDGSFLESKPVVHLNMMGQVTGKVVLTSFVFIALLEARESCINEVEGFTVVVEKAHGYLTSQAMNGLEDFPLAITAYALSLWKVSDGAAKVTMHTLKTSGLQTEELIHWGSNKGKAAAVESTAYGLLAAIQHEEGEIAEKATNWLSQSATFGGYFQSTQDTVMALQALTGFESCQSRMKKMDLSFKIRAEENGVFDKEFQITNDNAFVQKPFKVPVHGQLTVTASGTGQGILTFVKKYREKVVIKKDCKGFSLEITTNLDNQVKQRRRQSINPEFNVYRFIGCFRYLRNQEPGMVVMDISLPTGFEAKKKDLDDMKNLVDNYIVQYEIRPGRVFLYLDKVNKDEKNCVGFRLNQVFESNLVLPVTATVFEYYEPDFRCSKSYHPKMEVNPDASCHGNICNCLQRHCVELKGMADEDRNADRNGNACRAEYVFIIGVTKVTKTASYININAALKTVLKKGMDQAINVGARRSFVIPMHCGKNLNVSPGDIYLVMGMHNAHWRNSDRTQYVLTSDTWFEKFPLESVCRLPSPPASCQVSENFKGCSLKG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites