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Zona pellucida sperm-binding protein 4

Summary

UniProt ID

Q00193

Gene Symbol

ZP4
ZPB
ZPX

Organism

Oryctolagus cuniculus (rabbit)

External Links

Annotation

Keyword

Cell membrane
Cleavage on pair of basic residues
Direct protein sequencing
Disulfide bond
Extracellular matrix
Fertilization
Glycoprotein
Receptor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
prevention of polyspermy
acrosomal vesicle exocytosis
positive regulation of acrosome reaction
negative regulation of binding of sperm to zona pellucida
binding of sperm to zona pellucida
positive regulation of humoral immune response
positive regulation of T cell proliferation

Displaying **all 4** entries
GO Term
extracellular region
plasma membrane
collagen-containing extracellular matrix
egg coat

Displaying **all 3** entries
GO Term
identical protein binding
acrosin binding
structural constituent of egg coat

Annotation information from UniProt.

Sequence

MAPGSTMWLLGYIFLCFPVSFALIKQPKPETPTDPGVLHCRPWNFKFTINFQNQETGSSPVLVTWDNQGRLHRLQNDTDCGTRVGEGPGPSVVLEANYSSCYVTESEPYYVMLVGVEEVDAAGQNLVTKQQLLKCPMHLPAPDAGLCDSVPVQDRLPCATAPISQEDCEELGCCHSSEEVNACYYGNTVTSHCTQEGHFSIAVSRNVSSPPLHLDSVHLVFGNDSECQPVVATRAFVLFLFPFTACGTTRQITGDRAIYENELLATREVRTWSRGSITRDSIFRLRVSCSYSISSSALPVDMHVLTLPPPLPETQPGPLTVVLQIAKDKDYHSYYTMDDYPVVKLLRDPIYVDVSILYRTDPYLGLRLHQCWATPRTNPLYQPQWPILVKGCPYTGDNYQTQLIPVQEAFDLPFPSHHQRFSISTFSFLDSSVAKEALKGPIYLHCSVSVCQPTGTQSCTVTCPIDSRRRNSDINFQNSTANISSKGPMILLQATEDPSEKLHKHSGVPVHPGALWVAGLSGIFIIGALLVSYVAIRTRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
76	N-linked (GlcNAc...) asparagine	UniProt
97	N-linked (GlcNAc...) asparagine	UniProt
206	N-linked (GlcNAc...) asparagine	UniProt
223	N-linked (GlcNAc...) asparagine	UniProt
296	O-linked (GalNAc...) serine	UniProt
306	O-linked (GalNAc...) threonine	UniProt
478	N-linked (GlcNAc...) asparagine	UniProt
482	N-linked (GlcNAc...) asparagine	UniProt