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Sodium/calcium exchanger 1

Summary

UniProt ID

Q01728

Gene Symbol

Slc8a1
Ncx1

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q01728

Annotation

Keyword

Alternative splicing
Antiport
Calcium transport
Calmodulin-binding
Cell membrane
Cell projection
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Signal
Sodium transport
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 47 in total

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GO Term
regulation of calcium ion transport
muscle cell development
cardiac muscle cell development
cardiac muscle contraction
calcium ion transmembrane transport
negative regulation of cytosolic calcium ion concentration
cellular response to hypoxia
sodium ion import across plasma membrane
relaxation of smooth muscle
response to hypoxia

Displaying entries **1 - 10** of 20 in total

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GO Term
microtubule
plasma membrane
membrane
axon
synapse
postsynaptic membrane
cell periphery
dendrite
cell projection
neuronal cell body

Displaying **all 8** entries
GO Term
monoatomic ion antiporter activity involved in regulation of postsynaptic membrane potential
calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration
calcium ion binding
cytoskeletal protein binding
ankyrin binding
transmembrane transporter binding
calcium:sodium antiporter activity
calmodulin binding

Annotation information from UniProt.

Sequence

MLRLSLPPNVSMGFRLVTLVALLFTHVDHITADTEAETGGNETTECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVSSPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPASKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNMDVVENDPVSKVFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVIFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVRVSSEVSEDGILDSNHVSAIACLGSPNTATITIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIIPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFIEIGEPRLVEMSEKKALLLNELGGFTLTEGKKMYGQPVFRKVHARDHPIPSTVISISEEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSSLFVLLWLLYIFFSSLEAYCHIKGF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
41	N-linked (GlcNAc...) asparagine			UniProt
157	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Ion homeostasis	Rattus norvegicus
Reduction of cytosolic Ca++ levels	Rattus norvegicus
Sodium/Calcium exchangers	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements