Interferon-induced, double-stranded RNA-activated protein kinase

Summary
UniProt ID
Q03963
Gene Symbol
  • Eif2ak2
  • Pkr
  • Prkr
  • Tik
Organism
Mus musculus (house mouse)
External Links
GlyGen
Q03963
PubChem
Q03963
The O-GlcNAc Database
Q03963
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Acetylation
  • Antiviral defense
  • Cytoplasm
  • Innate immunity
  • Isopeptide bond
  • Nucleus
  • Phosphoprotein
  • RNA-binding
  • Reference proteome
  • Repeat
  • Serine/threonine-protein kinase
  • Transcription regulation
  • Tyrosine-protein kinase
  • Ubl conjugation
Gene Ontology (GO)
Sequence
MASDTPGFYMDKLNKYRQMHGVAITYKELSTSGPPHDRRFTFQVLIDEKEFPEAKGRSKQEARNAAAKLAVDILDNENKVDCHTSASEQGLFVGNYIGLVNSFAQKKKLSVNYEQCEPNSELPQRFICKCKIGQTMYGTGSGVTKQEAKQLAAKEAYQKLLKSPPKTAGTSSSVVTSTFSGFSSSSSMTSNGVSQSAPGSFSSENVFTNGLGENKRKSGVKVSPDDVQRNKYTLDARFNSDFEDIEEIGLGGFGQVFKAKHRIDGKRYAIKRVKYNTEKAEHEVQALAELNHVNIVQYHSCWEGVDYDPEHSMSDTSRYKTRCLFIQMEFCDKGTLEQWMRNRNQSKVDKALILDLYEQIVTGVEYIHSKGLIHRDLKPGNIFLVDERHIKIGDFGLATALENDGKSRTRRTGTLQYMSPEQLFLKHYGKEVDIFALGLILAELLHTCFTESEKIKFFESLRKGDFSNDIFDNKEKSLLKKLLSEKPKDRPETSEILKTLAEWRNISEKKKRNTC
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
ISG15 antiviral mechanism Mus musculus
PKR-mediated signaling Mus musculus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024