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ERAD-associated E3 ubiquitin-protein ligase component HRD3

Summary

UniProt ID

Q05787

Gene Symbol

HRD3

Organism

Saccharomyces cerevisiae S288C

External Links

PubChem: Q05787

Annotation

Keyword

3D-structure
Endoplasmic reticulum
Glycoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
retrograde protein transport, ER to cytosol
ERAD pathway
detection of unfolded protein
ubiquitin-dependent glycoprotein ERAD pathway
negative regulation of protein autoubiquitination

Displaying **all 6** entries
GO Term
Hrd1p ubiquitin ligase complex
Hrd1p ubiquitin ligase ERAD-M complex
Hrd1p ubiquitin ligase ERAD-L complex
endoplasmic reticulum
endoplasmic reticulum membrane
luminal surveillance complex

Annotation information from UniProt.

Sequence

MITLLLYLCVICNAIVLIRADSIADPWPEARHLLNTIAKSRDPMKEAAMEPNADEFVGFYVPMDYSPRNEEKNYQSIWQNEITDSQRHIYELLVQSSEQFNNSEATYTLSQIHLWSQYNFPHNMTLAHKYLEKFNDLTHFTNHSAIFDLAVMYATGGCASGNDQTVIPQDSAKALLYYQRAAQLGNLKAKQVLAYKYYSGFNVPRNFHKSLVLYRDIAEQLRKSYSRDEWDIVFPYWESYNVRISDFESGLLGKGLNSVPSSTVRKRTTRPDIGSPFIAQVNGVQMTLQIEPMGRFAFNGNDGNINGDEDDEDASERRIIRIYYAALNDYKGTYSQSRNCERAKNLLELTYKEFQPHVDNLDPLQVFYYVRCLQLLGHMYFTGEGSSKPNIHMAEEILTTSLEISRRAQGPIGRACIDLGLINQYITNNISQAISYYMKAMKTQANNGIVEFQLSKLATSFPEEKIGDPFNLMETAYLNGFIPAIYEFAVMIESGMNSKSSVENTAYLFKTFVDKNEAIMAPKLRTAFAALINDRSEVALWAYSQLAEQGYETAQVSAAYLMYQLPYEFEDPPRTTDQRKTLAISYYTRAFKQGNIDAGVVAGDIYFQMQNYSKAMALYQGAALKYSIQAIWNLGYMHEHGLGVNRDFHLAKRYYDQVSEHDHRFYLASKLSVLKLHLKSWLTWITREKVNYWKPSSPLNPNEDTQHSKTSWYKQLTKILQRMRHKEDSDKAAEDSHKHRTVVQNGANHRGDDQEEASEILGFQMEDLVTMGCILGIFLLSILMSTLAARRGWNVRFNGAQLNANGNRQQEQQQQQQAQGPPGWDFNVQIFAI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
101	N-linked (GlcNAc...) asparagine	UniProt
123	N-linked (GlcNAc...) asparagine	UniProt
142	N-linked (GlcNAc...) asparagine	UniProt
429	N-linked (GlcNAc...) asparagine	UniProt
611	N-linked (GlcNAc...) asparagine	UniProt