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Cyclic AMP-dependent transcription factor ATF-4

Summary

UniProt ID

Q06507

Gene Symbol

Atf4
Creb2

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q06507
PubChem: Q06507
The O-GlcNAc Database: Q06507

Annotation

Keyword

3D-structure
Acetylation
Activator
Biological rhythms
Cell membrane
Cytoskeleton
DNA-binding
Hydroxylation
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Repressor
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

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GO Term
regulation of DNA-templated transcription
regulation of transcription by RNA polymerase II
transcription by RNA polymerase II
circadian rhythm
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
positive regulation of vascular endothelial growth factor production
endoplasmic reticulum unfolded protein response
response to endoplasmic reticulum stress
circadian regulation of gene expression

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GO Term
protein-containing complex
dendrite membrane
Lewy body core
ATF4-CREB1 transcription factor complex
ATF1-ATF4 transcription factor complex
CHOP-ATF4 complex
nuclear speck
cytoplasm
nucleus
nuclear periphery

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GO Term
protein kinase binding
RNA polymerase II-specific DNA-binding transcription factor binding
DNA-binding transcription factor binding
promoter-specific chromatin binding
identical protein binding
leucine zipper domain binding
protein heterodimerization activity
RNA polymerase II transcription regulatory region sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity

Annotation information from UniProt.

Sequence

MTEMSFLNSEVLAGDLMSPFDQSGLGAEESLGLLDDYLEVAKHLKPHGFSSDKAGSSEWPAMDDGLASASDTGKEDAFSGTDWMLEKMDLKEFDFDALFRMDDLETMPDELLTTLDDTCDLFAPLVQETNKEPPQTVNPIGHLPESLIKVDQVAPFTFLQPFPCSPGVLSSTPEHSFSLELGSEVDISEGDRKPDSAAYITLIPPCVKEEDTPSDNDSGICMSPESYLGSPQHSPSTSRAPPDNLPSPGGSRGSPRPKPYDPPGVSLTAKVKTEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKEKADSLAKEIQYLKDLIEEVRKARGKKRVP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites