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ATP-dependent DNA repair protein/ubiquitin-protein ligase E3 IRC20

Summary

UniProt ID: Q06554
Gene Symbol: IRC20 YLR247C
Gene ID: 850949
Organism: Saccharomyces cerevisiae S288C

External Links

GlyGen: Q06554
O-GlcNAcAtlas: Q06554
Re-Glyco: Q06554

Annotation

Keyword: Acetylation DNA recombination DNA repair Hydrolase Magnesium Multifunctional enzyme Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation Zinc-finger

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
DNA repair
double-strand break repair via nonhomologous end joining	IGI	PMID
double-strand break repair via synthesis-dependent strand annealing	IMP	PMID PMID
double-strand break repair via synthesis-dependent strand annealing	IGI	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via synthesis-dependent strand annealing

double-strand break repair via nonhomologous end joining

Displaying **all 3** entries
GO Term	Evidence Code	Reference
nucleus	IEA	GO_REF
nucleus	HDA	PMID
mitochondrion	HDA	PMID PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
magnesium ion binding	NAS	PMID
DNA binding	IDA	PMID
helicase activity	ISS	PMID
ubiquitin-protein transferase activity	IDA	PMID
ubiquitin-protein transferase activity	IMP	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

isomerase activity [inference]

macromolecular conformation isomerase activity [inference]

nucleic acid conformation isomerase activity [inference]

helicase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

catalytic activity, acting on a nucleic acid [inference]

helicase activity

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA

binding [inference]

nucleic acid binding [inference]

DNA binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

transition metal ion binding [inference]

zinc ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSAVGALLAREYNVTAEKCDFFLENGSFDSVIAALPALNQEQETVTQKVSKNGKELINVASVNIEIPERISLSNNGRQLFKFIVDIEILPCENDNEATLVVSSDSVSLFQIGFKMENNSKIAVDKQLPLILDICAHKNQERALRNQLENRKSLERKPSRKRRKKNSNVNDPEKLLKSRIHELSLSYKDFECSPVVFRYNDSSLTWVLSFNLKLKFLNNKFNRFSVEANQILDLTFSNRDENEFERYHKHSHIHSNFIQKQFISQILEYSKDRLSKIKPFLPQSIPDLKVNLLPFQRESVEWMLIKEGHGNSLSDTPTVIDEVGLIDFMNEYYAYGYELIARSPDEVGPSLLWNKLTGYILTTEDAAHLYNQYRKERLSGDYPVCAKGVLAEEMGLGKTIEILSLILLNRRKLKDSEATFIDDENRTITKTKTTLIICPNAILKQWLEEIELHANSLKWYTYRGYNEIMKDCKTVDEAVQQLCQYDIIVTSYNIIATEVHHAEFNRSIRSRRLKSPKYDYSSPLALMQFYRIILDEVQMLRSSSTYSAKCTSLLHRIHTWGVSGTPIQNIYNFRMIMSYLKLHPFCDEVDFIRTLQEEIKLRNEAKDYTSNDFVCQLKGVRFSIKDCMNIFYRYDLCIRHSKANVASQIHIPRQHNFIIPLEFAPIEWDNYLNLWNNFLELSGYNSDGSGSPRVSNAFLNEWLSRLRYICCHALFPEILSTRQKRLHGHLSRISNIDDILISMRMDAFDSLIGYYRERFHLSIKQAQYELEISNTPAKALESFIKIRDDLMIHIRQKFNVEDPFDKSLNLSEDEDEHMDERFGEKETSSGDESDREINGAKNHDNHNNDGMLSNHLKKKGLRAMMNLLHDCYFFLGSVYYNLGTRKLEEADDKHRKEKTEEVVYSDVFPKNELEEIEENRLLEQENYANAEILRKSILSSEARKVDMTIKMARTKFAPMTSNIPLRLINIEFDHKNDYSSNLAVSRCFKSLSKLIEGLNEQTKNFNELLDELLIIIYEPVHRTEDDDSTNKIIGNEEYSTSIDSQDKIFSLLGCLEIILQNRDNILTSESEVKIPKHLVPEGSIISKYQKQLLNSLRLISGTPLRTVFDELKNSRIVRRISSSNESESTIQNFEDYLLQYEVESKSLFKYNKQVRESLKILGSIYNAKTEYYSQLQRISDSLVSLHSLSAPQLSHLIRTINKSLGGTLDAKINNIESRLIYLKNLSRLKDTLNDNQILSCSICLGEVEIGAIIKCGHYFCKSCILTWLRAHSKCPICKGFCSISEVYNFKFKNSTEKREKEIQEPRREGADSSQDNSNENSIISNMSEVEKLFGNKYEQFHQINEVHQIHIKESFGAKIDFVIKLISYLRLKSEQENADPPQVILYSQKTEYLKVIGKVLKLYHIEHLACLSNTANVGETINNFKRQPSVTCLLLNVKTLGAGLNLINAKHIFLLDPILNNSDELQAMGRNNRIGQDEETFVWNFMIRNTVEENILRYKCILEERKRKEKSKKGDKYDEAQDETDNEESDDAKFEISVVDQEVSNEHLWNCFFHGSD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites