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Clusterin

Summary

UniProt ID

Q06890

Gene Symbol

Apoj
Clu
Msgp-2

Gene ID

12759

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003921

GlyConnect

Clusterin

GlyGen

Q06890

PubChem

Q06890

The O-GlcNAc Database

Q06890

RaftProt

Q06890

Re-Glyco

Q06890

Annotation

Keyword

Chaperone
Cytoplasm
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Membrane
Microsome
Mitochondrion
Nucleus
Phosphoprotein
Reference proteome
Secreted
Signal
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 17 in total

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GO Term
extracellular space
nucleus
cytoplasm
mitochondrion
mitochondrial inner membrane
cytoskeleton
intracellular membrane-bounded organelle
synapse
cell periphery
cytosol

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 33 in total

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GO Term
regulation of amyloid-beta clearance
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of neurofibrillary tangle assembly
negative regulation of response to endoplasmic reticulum stress
positive regulation of ubiquitin-dependent protein catabolic process
positive regulation of intrinsic apoptotic signaling pathway
cell morphogenesis
microglial cell activation
negative regulation of protein-containing complex assembly
positive regulation of proteasomal ubiquitin-dependent protein catabolic process

Displaying **all 9** entries
GO Term
unfolded protein binding
protein carrier chaperone
amyloid-beta binding
ubiquitin protein ligase binding
protein-containing complex binding
low-density lipoprotein particle receptor binding
misfolded protein binding
receptor ligand activity
tau protein binding

Annotation information from UniProt.

Sequence

MKILLLCVALLLIWDNGMVLGEQEVSDNELQELSTQGSRYINKEIQNAVQGVKHIKTLIEKTNAERKSLLNSLEEAKKKKEDALEDTRDSEMKLKAFPEVCNETMMALWEECKPCLKHTCMKFYARVCRSGSGLVGQQLEEFLNQSSPFYFWMNGDRIDSLLESDRQQSQVLDAMQDSFARASGIIDTLFQDRFFARELHDPHYFSPIGFPHKRPHFLYPKSRLVRSLMSPSHYGPPSFHNMFQPFFEMIHQAQQAMDVQLHSPAFQFPDVDFLREGEDDRTVCKEIRRNSTGCLKMKGQCEKCQEILSVDCSTNNPAQANLRQELNDSLQVAERLTEQYKELLQSFQSKMLNTSSLLEQLNDQFNWVSQLANLTQGEDKYYLRVSTVTTHSSDSEVPSRVTEVVVKLFDSDPITVVLPEEVSKDNPKFMDTVAEKALQEYRRKSRAE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
102	N-linked (GlcNAc...) asparagine		G46503DX	GlycoProtDB UniProt GlyGen
144	N-linked (GlcNAc...) asparagine			UniProt GlyGen
290	N-linked (GlcNAc...) asparagine	17330941	G00912UN G70101JE	UniProt GlyGen GlyConnect
327	N-linked (GlcNAc...) asparagine	16944957	G08673AT G31966KA G15569GG G40608DF G70101JE G64527OM G05724UK G31852PQ	GlycoProtDB UniProt GlyGen GlyConnect
329			G49108TO	The O-GlcNAc Database
353	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
373	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Antimicrobial peptides	Mus musculus
Platelet degranulation	Mus musculus
Regulation of Complement cascade	Mus musculus
Terminal pathway of complement	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements