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Transforming growth factor beta-2 proprotein

Summary

UniProt ID

Q07257

Gene Symbol

Tgfb2

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q07257

Annotation

Keyword

Alternative splicing
Cleavage on pair of basic residues
Disulfide bond
Extracellular matrix
Glycoprotein
Growth factor
Mitogen
Reference proteome
Signal

Gene Ontology (GO)

Displaying entries **91 - 100** of **130** in total

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GO Term
embryonic digestive tract development
embryonic neurocranium morphogenesis
regulation of timing of catagen
positive regulation of timing of catagen
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
positive regulation of SMAD protein signal transduction
secondary palate development
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
embryonic limb morphogenesis
negative regulation of release of sequestered calcium ion into cytosol

Displaying entries **1 - 10** of 11 in total

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GO Term
extracellular region
basement membrane
extracellular space
secretory granule
axon
extracellular matrix
collagen-containing extracellular matrix
neuronal cell body
endosome
trans-Golgi network

Displaying **all 10** entries
GO Term
signaling receptor binding
protein-containing complex binding
identical protein binding
protein homodimerization activity
cytokine activity
amyloid-beta binding
type II transforming growth factor beta receptor binding
transforming growth factor beta receptor binding
growth factor activity
type III transforming growth factor beta receptor binding

Annotation information from UniProt.

Sequence

MHYCVLRTFLLLHLVPVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPDEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSHFPSETVCPVVTTSSGSVGSFCSIQSQVLCGYLDAIPPTFYRPYFRIVRFDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFIPSNNYIIPNKSQELEARFAGIDGTSTYASGDQKTIKSTRKKSSGKTPHLLLMLLPSYRLESQQSSRRRKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHTKVLSLYNTINPEASASPCCVSQDLEPLTILYYIGNTPKIEQLSNMIVKSCKCS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
72	N-linked (GlcNAc...) asparagine	UniProt
168	N-linked (GlcNAc...) asparagine	UniProt
269	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Molecules associated with elastic fibres	Rattus norvegicus
Platelet degranulation	Rattus norvegicus
TGF-beta receptor signaling activates SMADs	Rattus norvegicus