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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor homolog 1
Summary
- UniProt ID
- Q07407
- Gene Symbol
-
- htl
- FR1
- Tk1
- Organism
- Drosophila melanogaster (fruit fly)
External Links
- PubChem
- Q07407
Annotation
- Keyword
-
- ATP-binding
- Developmental protein
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| receptor complex |
| postsynapse of neuromuscular junction |
| GO Term |
|---|
| transmembrane receptor protein tyrosine kinase activity |
| fibroblast growth factor receptor activity |
| ATP binding |
| protein tyrosine kinase activity |
Sequence
MAAAWSWRASHSTITMTSGSLVVLFLLLSIWQPAVQVEGRRQMANSQEMIKDHLGARSQNKTPAITNNANQSSTSSADLDDGAADDDDNKADLPVNVSSKPYWRNPKKMSFLQTRPSGSLLTLNCHALGNPEPNITWYRNGTVDWTRGYGSLKRNRWTLTMEDLVPGDCGNYTCKVCNSLGCIRHDTQVIVSDRVNHKPILMTGPLNLTLVVNSTGSMHCKYLSDLTSKKAWIFVPCHGMTNCSNNRSIIAEDKDQLDFVNVRMEQEGWYTCVESNSLGQSNSTAYLRVVRSLHVLEAGVASGSLHSTSFVYIFVFGGLIFIFMTTLFVFYAIRKMKHEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGSMDTMIMPVVRIQKQRTTVLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAEVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKEDYLDVDIANLDTPPSTSDEEEDETDNLQKWCNY
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 70 | N-linked (GlcNAc...) asparagine |
|
||
| 96 | N-linked (GlcNAc...) asparagine |
|
||
| 134 | N-linked (GlcNAc...) asparagine |
|
||
| 140 | N-linked (GlcNAc...) asparagine |
|
||
| 171 | N-linked (GlcNAc...) asparagine |
|
||
| 207 | N-linked (GlcNAc...) asparagine |
|
||
| 213 | N-linked (GlcNAc...) asparagine |
|
||
| 242 | N-linked (GlcNAc...) asparagine |
|
||
| 246 | N-linked (GlcNAc...) asparagine |
|
||
| 282 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Negative regulation of FGFR4 signaling | Drosophila melanogaster |
| PI-3K cascade:FGFR2 | Drosophila melanogaster |
| PI-3K cascade:FGFR3 | Drosophila melanogaster |
| PI-3K cascade:FGFR4 | Drosophila melanogaster |
| PI3K Cascade | Drosophila melanogaster |
| PI3K/AKT Signaling | Drosophila melanogaster |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Drosophila melanogaster |
| Phospholipase C-mediated cascade; FGFR2 | Drosophila melanogaster |
| Phospholipase C-mediated cascade; FGFR3 | Drosophila melanogaster |
| Phospholipase C-mediated cascade; FGFR4 | Drosophila melanogaster |
