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Leukocyte surface antigen CD47

Summary

UniProt ID

Q08722

Gene Symbol

CD47
MER6

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011808

GlyConnect

1456

GlyGen

Q08722

PubChem

Q08722

The O-GlcNAc Database

Q08722

RaftProt

Q08722

Annotation

Keyword

3D-structure
Alternative splicing
Angiogenesis
Apoptosis
Cell adhesion
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Inflammatory response
Phosphoprotein
Pyrrolidone carboxylic acid
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **11 - 20** of 24 in total

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GO Term
regulation of tumor necrosis factor production
regulation of nitric oxide biosynthetic process
negative regulation of phagocytosis
positive regulation of phagocytosis
positive regulation of T cell activation
positive regulation of stress fiber assembly
regulation of Fc receptor mediated stimulatory signaling pathway
cellular response to type II interferon
positive regulation of monocyte extravasation
integrin-mediated signaling pathway

Displaying **all 5** entries
GO Term
plasma membrane
extracellular exosome
tertiary granule membrane
cell surface
specific granule membrane

Displaying **all 3** entries
GO Term
cell-cell adhesion mediator activity
thrombospondin receptor activity
protein binding involved in heterotypic cell-cell adhesion

Annotation information from UniProt.

Sequence

MWPLVAALLLGSACCGSAQLLFNKTKSVEFTFCNDTVVIPCFVTNMEAQNTTEVYVKWKFKGRDIYTFDGALNKSTVPTDFSSAKIEVSQLLKGDASLKMDKSDAVSHTGNYTCEVTELTREGETIIELKYRVVSWFSPNENILIVIFPIFAILLFWGQFGIKTLKYRSGGMDEKTIALLVAGLVITVIVIVGAILFVPGEYSLKNATGLGLIVTSTGILILLHYYVFSTAIGLTSFVIAILVIQVIAYILAVVGLSLCIAACIPMHGPLLISGLSILALAQLLGLVYMKFVASNQKTIQPPRKAVEEPLNAFKESKGMMNDE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
23	N-linked (GlcNAc...) asparagine	18657508		UniProt GlyGen
34			G76535FN	UniProt GlyGen
50	N-linked (GlcNAc...) asparagine	18657508 19349973	G31852PQ	UniProt GlyGen
67			G49108TO	GlyGen The O-GlcNAc Database
73	N-linked (GlcNAc...) asparagine	18657508 19159218 19349973	G27947YN G33416PL G45395BF G31986NC G40574BA G00912UN G49906RN G70441OD G66760KM G83646BJ G36442WJ G15664MX G66621EA G80223IX G25418HZ G27126ED G27058EU G39619TI G10773YW G96091TT G51640FO G60033FS G49018RC G72747WU G59626AS G92406TI G20210JR G41840AI G01650EU G23294PN G48584BU G80920RR G47702MW G92062TF G63041LO G02886BB G90659AW G03574QJ G59924QI G84820NF G37399XV G82463GQ G62765YT G64527OM G47644PP G10486CT G28541PG G72735IY G18647XP G95865ZB G05724UK G31852PQ G39446WN G11314AS G39188ZX G41247ZX G02815KT G06110VR G92050GC	GlycoProtDB UniProt GlyGen GlyConnect
111	N-linked (GlcNAc...) asparagine	18657508 19159218	G89827JR G57776ZS G87123QX G79666IR G85554PZ G10819WX G27915IV G70441OD G87661QW G83646BJ G27058EU G10488MI G60033FS G41071NU G07755XJ G86182NS G70619PT G47702MW G63041LO G65184UU G42124LM G90659AW G29299MO G37399XV G62765YT G47644PP G72790NZ G95177YH G10486CT G05049YU G28541PG G18647XP G95865ZB G31852PQ G72787SB G39446WN G11314AS G41247ZX G57776ZU G36379GD G02815KT G57317CE G92275SC	GlycoProtDB UniProt GlyGen
206	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Cell surface interactions at the vascular wall	Homo sapiens
Integrin cell surface interactions	Homo sapiens
Neutrophil degranulation	Homo sapiens
Signal regulatory protein family interactions	Homo sapiens

Human Protein Atlas

ENSG00000196776

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements