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Tripeptidyl-peptidase 1

Summary

UniProt ID

Q0V8B6

Gene Symbol

CLN2
TPP1

Gene ID

515575

Organism

Bos taurus (domestic cattle)

External Links

PubChem: Q0V8B6
Re-Glyco: Q0V8B6

Annotation

Keyword

Autocatalytic cleavage
Calcium
Disulfide bond
Glycoprotein
Lysosome
Metal-binding
Reference proteome
Serine protease
Signal
Zymogen

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
lysosome
melanosome
Golgi apparatus
membrane raft
recycling endosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 5** entries
GO Term
peptide catabolic process
proteolysis
nervous system development
central nervous system development
bone resorption

Displaying **all 6** entries
GO Term
serine-type endopeptidase activity
metal ion binding
lysophosphatidic acid binding
sulfatide binding
endopeptidase activity
tripeptidyl-peptidase activity

Annotation information from UniProt.

Sequence

MGPRSGLLGLFALFVAGKCSYSPEPDQQRRLPPGWVSLGRADPEEELSLTFALRQQNVKRLSELVQAVSDPGSPRYGKYLTLEDVAELVRPSPLTLHTVQKWLLAAGARNCHSVTTQDFLTCWLSVRQAELLLSGAEFHHYVGGPAETHAVRSLHPYRLPKALAPHVDFVGGLHRFPPTSTLRQHPEPQVPGTVGLHLGVTPSVIRKRYNLTAQDVGSGTTNNSQACAQFLEQYFHDSDLAEFMRLFGGDFAHQASVARVVGQQGRGRAGIEASLDVEYLMSAGANISTWVYSSPGRHESQEPFLQWLLLLSNESALPYVHTVSYGDDEDSLSSTYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSGRHQFRPSFPASSPYVTTVGGTSFQNPFRVTDEVVDYISGGGFSNVFPRPSYQEEAVTRYLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNHVPIPWVSGTSASTPVFGGLLSLINEHRILRGLPPLGFLNPRLYQKHGAGLFDVTRGCHESCLNEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLMNP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
210	N-linked (GlcNAc...) asparagine	UniProt
222	N-linked (GlcNAc...) asparagine	UniProt
286	N-linked (GlcNAc...) asparagine	UniProt
313	N-linked (GlcNAc...) asparagine	UniProt
443	N-linked (GlcNAc...) asparagine	UniProt