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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Polypeptide N-acetylgalactosaminyltransferase 1
Summary
- UniProt ID
- Q10472
- Gene Symbol
-
- GALNT1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Disulfide bond
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Lectin
- Manganese
- Metal-binding
- Reference proteome
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| carbohydrate binding |
| manganese ion binding |
| polypeptide N-acetylgalactosaminyltransferase activity |
Sequence
MRKFAYCKVVLATSLIWVLLDMFLLLYFSECNKCDEKKERGLPAGDVLEPVQKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCNGSRSQQWLLRNVTLPEIF
Glycosylation Sites
G70441OD
G45395BF
G08918WF
G27058EU
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| COPI-independent Golgi-to-ER retrograde traffic | Homo sapiens |
| Maturation of protein 3a | Homo sapiens |
| Maturation of protein 3a | Homo sapiens |
| O-linked glycosylation of mucins | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080199 | colorectal carcinoma | |
| DOID:10534 | stomach cancer | |
| DOID:1682 | congenital heart disease | |
| DOID:2394 | ovarian cancer | |
| DOID:3571 | liver cancer | |
| DOID:4001 | ovarian carcinoma | |
| DOID:4079 | heart valve disease | |
| DOID:5517 | stomach carcinoma | |
| DOID:5672 | large intestine cancer | |
| DOID:6000 | congestive heart failure |
