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Forkhead box protein C1

Summary

UniProt ID

Q12948

Gene Symbol

FKHL7
FOXC1
FREAC3

Gene ID

2296

Organism

Homo sapiens (human)

External Links

GlyGen: Q12948
The O-GlcNAc Database: Q12948
O-GlcNAcAtlas: Q12948
Re-Glyco: Q12948

Annotation

Keyword

Activator
Angiogenesis
DNA-binding
Deafness
Developmental protein
Disease variant
Nucleus
Peters anomaly
Phosphoprotein
Reference proteome
Repressor
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
chromatin
heterochromatin
nucleus
nucleoplasm
cytosol

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 56 in total

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GO Term
positive regulation of core promoter binding
negative regulation of transcription by RNA polymerase II
eye development
ureteric bud development
kidney development
lymph vessel development
regulation of transcription by RNA polymerase II
positive regulation of hematopoietic progenitor cell differentiation
angiogenesis
in utero embryonic development

Displaying entries **1 - 10** of 12 in total

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GO Term
DNA binding, bending
RNA polymerase II transcription regulatory region sequence-specific DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA binding
DNA-binding transcription factor activity
sequence-specific DNA binding
RNA polymerase II-specific DNA-binding transcription factor binding
DNA-binding transcription factor binding

Annotation information from UniProt.

Sequence

MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKEEKDRLHLKEPPPPGRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAPGGAGGSAVDDPLPDYSLPPVTSSSSSSLSHGGGGGGGGGGQEAGHHPAAHQGRLTSWYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNSPVNGNSSCQMAFPSSQSLYRTSGAFVYDCSKF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	GlyTouCan ID	Source
298	G49108TO	The O-GlcNAc Database
305	G49108TO	The O-GlcNAc Database
320	G49108TO	GlyGen The O-GlcNAc Database
323	G49108TO	GlyGen The O-GlcNAc Database
335	G49108TO	GlyGen
339	G49108TO	GlyGen The O-GlcNAc Database
340	G49108TO	GlyGen The O-GlcNAc Database
519	G23719VF	GlyGen
526	G59324HL	GlyGen

Feature

Domains & sites

PTM

ProtVista

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Formation of intermediate mesoderm	Homo sapiens
Formation of the ureteric bud	Homo sapiens

Disease

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0080608	anterior segment dysgenesis 3	Alliance of Genome Resources
DOID:0110122	Axenfeld-Rieger syndrome type 3	Alliance of Genome Resources
DOID:14686	Axenfeld-Rieger syndrome	Alliance of Genome Resources
DOID:1686	glaucoma	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements