GlyCosmos Portal

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Pappalysin-1

Summary

UniProt ID

Q13219

Gene Symbol

PAPPA

Organism

Homo sapiens (human)

External Links

GlyConnect

1594

GlyGen

Q13219

Annotation

Keyword

3D-structure
Direct protein sequencing
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Repeat
Secreted
Signal
Sushi
Zinc
Zymogen

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
protein catabolic process
proteolysis
cell surface receptor signaling pathway
female pregnancy
response to follicle-stimulating hormone
response to dexamethasone

Displaying **all 2** entries
GO Term
extracellular region
extracellular space

Displaying **all 3** entries
GO Term
zinc ion binding
metalloendopeptidase activity
metallopeptidase activity

Annotation information from UniProt.

Sequence

MRLWSWVLHLGLLSAALGCGLAERPRRARRDPRAGRPPRPAAGPATCATRAARGRRASPPPPPPPGGAWEAVRVPRRRQQREARGATEEPSPPSRALYFSGRGEQLRLRADLELPRDAFTLQVWLRAEGGQRSPAVITGLYDKCSYISRDRGWVVGIHTISDQDNKDPRYFFSLKTDRARQVTTINAHRSYLPGQWVYLAATYDGQFMKLYVNGAQVATSGEQVGGIFSPLTQKCKVLMLGGSALNHNYRGYIEHFSLWKVARTQREILSDMETHGAHTALPQLLLQENWDNVKHAWSPMKDGSSPKVEFSNAHGFLLDTSLEPPLCGQTLCDNTEVIASYNQLSSFRQPKVVRYRVVNLYEDDHKNPTVTREQVDFQHHQLAEAFKQYNISWELDVLEVSNSSLRRRLILANCDISKIGDENCDPECNHTLTGHDGGDCRHLRHPAFVKKQHNGVCDMDCNYERFNFDGGECCDPEITNVTQTCFDPDSPHRAYLDVNELKNILKLDGSTHLNIFFAKSSEEELAGVATWPWDKEALMHLGGIVLNPSFYGMPGHTHTMIHEIGHSLGLYHVFRGISEIQSCSDPCMETEPSFETGDLCNDTNPAPKHKSCGDPGPGNDTCGFHSFFNTPYNNFMSYADDDCTDSFTPNQVARMHCYLDLVYQGWQPSRKPAPVALAPQVLGHTTDSVTLEWFPPIDGHFFERELGSACHLCLEGRILVQYASNASSPMPCSPSGHWSPREAEGHPDVEQPCKSSVRTWSPNSAVNPHTVPPACPEPQGCYLELEFLYPLVPESLTIWVTFVSTDWDSSGAVNDIKLLAVSGKNISLGPQNVFCDVPLTIRLWDVGEEVYGIQIYTLDEHLEIDAAMLTSTADTPLCLQCKPLKYKVVRDPPLQMDVASILHLNRKFVDMDLNLGSVYQYWVITISGTEESEPSPAVTYIHGSGYCGDGIIQKDQGEQCDDMNKINGDGCSLFCRQEVSFNCIDEPSRCYFHDGDGVCEEFEQKTSIKDCGVYTPQGFLDQWASNASVSHQDQQCPGWVIIGQPAASQVCRTKVIDLSEGISQHAWYPCTISYPYSQLAQTTFWLRAYFSQPMVAAAVIVHLVTDGTYYGDQKQETISVQLLDTKDQSHDLGLHVLSCRNNPLIIPVVHDLSQPFYHSQAVRVSFSSPLVAISGVALRSFDNFDPVTLSSCQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTVRDIPHWLNPTRVERVVCTAGLKWYPHPALIHCVKGCEPFMGDNYCDAINNRAFCNYDGGDCCTSTVKTKKVTPFPMSCDLQGDCACRDPQAQEHSRKDLRGYSHG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 14 in total

1

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Position	Description	PubMed ID	GlyTouCan ID	Source
390	N-linked (GlcNAc...) asparagine			UniProt GlyGen
402	N-linked (GlcNAc...) asparagine	12421832		UniProt GlyGen
429	N-linked (GlcNAc...) asparagine	12421832	G46503DX G80920RR G90659AW G62765YT G31852PQ G23719VF G41247ZX G02815KT G06110VR	UniProt GlyGen GlyConnect
480	N-linked (GlcNAc...) asparagine	12421832	G80920RR	UniProt GlyGen
601	N-linked (GlcNAc...) asparagine	12421832	G80920RR	UniProt GlyGen
619	N-linked (GlcNAc...) asparagine	12421832		UniProt GlyGen
725	N-linked (GlcNAc...) asparagine	12421832		UniProt GlyGen
825	N-linked (GlcNAc...) asparagine			UniProt GlyGen
1026	N-linked (GlcNAc...) asparagine	12421832		UniProt GlyGen
1222	N-linked (GlcNAc...) asparagine		G70696MD	UniProt GlyGen