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MIRAGE
S-phase kinase-associated protein 2
Summary
- UniProt ID
- Q13309
- Gene Symbol
-
- FBXL1
- SKP2
- Gene ID
- 6502
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Antiviral defense
- Cytoplasm
- Direct protein sequencing
- Host-virus interaction
- Innate immunity
- Leucine-rich repeat
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Ubl conjugation
- Ubl conjugation pathway
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| nucleolus |
| nucleoplasm |
| cytosol |
| SCF ubiquitin ligase complex |
| GO Term |
|---|
| ubiquitin ligase-substrate adaptor activity |
| identical protein binding |
Sequence
MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLGHPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 34 |
|
|||
| 210 |
|
G49108TO
G83460ZZ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | Homo sapiens |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | Homo sapiens |
| Antigen processing: Ubiquitination & Proteasome degradation | Homo sapiens |
| Cyclin D associated events in G1 | Homo sapiens |
| Neddylation | Homo sapiens |
| Orc1 removal from chromatin | Homo sapiens |
| Regulation of BACH1 activity | Homo sapiens |
| Regulation of RUNX2 expression and activity | Homo sapiens |
| SCF(Skp2)-mediated degradation of p27/p21 | Homo sapiens |
| Ub-specific processing proteases | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10286 | prostate carcinoma |
