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Transforming growth factor beta activator LRRC32

Summary

UniProt ID

Q14392

Gene Symbol

D11S833E
LRRC32

Gene ID

2615

Organism

Homo sapiens (human)

External Links

GlyGen: Q14392
PubChem: Q14392
The Human Metabolome Database: HMDBP14558
The O-GlcNAc Database: Q14392
RaftProt: Q14392
Re-Glyco: Q14392

Annotation

Keyword

3D-structure
Cell membrane
Disease variant
Disulfide bond
Glycoprotein
Growth factor binding
Intellectual disability
Leucine-rich repeat
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
extracellular space
plasma membrane
extracellular matrix
nucleoplasm
external side of plasma membrane
cell surface

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 6** entries
GO Term
negative regulation of cytokine production
negative regulation of activated T cell proliferation
secondary palate development
positive regulation of gene expression
establishment of protein localization to extracellular region
transforming growth factor beta receptor signaling pathway

Displaying **all 2** entries
GO Term
transforming growth factor beta binding
receptor ligand inhibitor activity

Annotation information from UniProt.

Sequence

MRPQILLLLALLTLGLAAQHQDKVPCKMVDKKVSCQVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSHLPAWTQAVSLEVLDLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLICRFSSQEEVSLSHVRPEDCEKGGLKNINLIIILTFILVSAILLTTLAACCCVRRQKFNQQYKA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
203	N-linked (GlcNAc...) asparagine		G99668VU G80479JV G26330YA G83460ZZ G46503DX G80920RR G62765YT	UniProt GlyGen
271	N-linked (GlcNAc...) asparagine		G83460ZZ G80920RR	UniProt GlyGen
308	N-linked (GlcNAc...) asparagine	19159218		UniProt GlyGen
345	N-linked (GlcNAc...) asparagine			UniProt GlyGen
371			G49108TO	The O-GlcNAc Database
377			G49108TO	The O-GlcNAc Database
545	N-linked (GlcNAc...) asparagine			UniProt GlyGen