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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Neutral alpha-glucosidase AB
Summary
- UniProt ID
- Q14697
- Gene Symbol
-
- GANAB
- G2AN
- KIAA0088
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Glycosidase
- Golgi apparatus
- Phosphoprotein
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| carbohydrate metabolic process |
| N-glycan processing |
| GO Term |
|---|
| endoplasmic reticulum lumen |
| Golgi apparatus |
| membrane |
| melanosome |
| intracellular membrane-bounded organelle |
| extracellular exosome |
| glucosidase II complex |
| GO Term |
|---|
| RNA binding |
| carbohydrate binding |
| alpha-glucosidase activity |
| glucan 1,3-alpha-glucosidase activity |
Sequence
MAAVAAVAARRRRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPYRALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLVADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEHQRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYGPMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVPVLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDSGYRVHEELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVWNDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIWIERVVIIGAGKPAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHLR
Glycosylation Sites
G80920RR
G62765YT
G31852PQ
G41247ZX
G02815KT
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Calnexin/calreticulin cycle | Homo sapiens |
| Maturation of spike protein | Homo sapiens |
| Maturation of spike protein | Homo sapiens |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050770 | polycystic liver disease | |
| DOID:0050778 | Meckel syndrome | |
| DOID:0060262 | gallbladder disease | |
| DOID:0110858 | polycystic kidney disease 1 | |
| DOID:0110859 | polycystic kidney disease 2 | |
| DOID:0110860 | polycystic kidney disease 3 | |
| DOID:2377 | multiple sclerosis | |
| DOID:322 | myelitis | |
| DOID:381 | arthropathy | |
| DOID:409 | liver disease |
