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[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial

Summary

UniProt ID

Q15120

Gene Symbol

PDHK3
PDK3

Gene ID

5165

Organism

Homo sapiens (human)

External Links

PubChem: Q15120
The Human Metabolome Database: HMDBP01508
The O-GlcNAc Database: Q15120
Re-Glyco: Q15120

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Charcot-Marie-Tooth disease
Disease variant
Kinase
Mitochondrion
Neurodegeneration
Reference proteome
Transit peptide

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
nucleolus
mitochondrion
mitochondrial matrix

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 8** entries
GO Term
regulation of reactive oxygen species metabolic process
regulation of glucose metabolic process
peptidyl-serine phosphorylation
hypoxia-inducible factor-1alpha signaling pathway
peroxisome proliferator activated receptor signaling pathway
cellular response to glucose stimulus
cellular response to fatty acid
regulation of acetyl-CoA biosynthetic process from pyruvate

Displaying **all 4** entries
GO Term
protein kinase activity
protein serine/threonine kinase activity
ATP binding
pyruvate dehydrogenase (acetyl-transferring) kinase activity

Annotation information from UniProt.

Sequence

MRLFRWLLKQPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPQVLDNFLQVLIKVRNRHNDVVPTMAQGVIEYKEKFGFDPFISTNIQYFLDRFYTNRISFRMLINQHTLLFGGDTNPVHPKHIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYEDRKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYSTAPRPSLEPTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKAKQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites