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Receptor-type tyrosine-protein phosphatase O

Summary

UniProt ID

Q16827

Gene Symbol

PTPRO
GLEPP1
PTPU2

Organism

Homo sapiens (human)

External Links

GlyGen: Q16827
PubChem: Q16827
The Human Metabolome Database: HMDBP08948
The O-GlcNAc Database: Q16827
O-GlcNAcAtlas: Q16827

Annotation

Keyword

3D-structure
Alternative splicing
Glycoprotein
Phosphoprotein
Protein phosphatase
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 16 in total

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GO Term
axon guidance
monocyte chemotaxis
regulation of glomerular filtration
negative regulation of glomerular filtration
cell morphogenesis
negative regulation of canonical Wnt signaling pathway
protein dephosphorylation
negative regulation of cell-substrate adhesion
negative regulation of neuron projection development
lamellipodium assembly

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GO Term
extracellular exosome
postsynaptic density membrane
glutamatergic synapse
GABA-ergic synapse
apical plasma membrane
plasma membrane
membrane
axon
neuron projection
lamellipodium

Displaying **all 6** entries
GO Term
protein homodimerization activity
cadherin binding
transmembrane receptor protein tyrosine phosphatase activity
Wnt-protein binding
phosphatase activity
protein tyrosine phosphatase activity

Annotation information from UniProt.

Sequence

MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISPASVYVVKITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFNHWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNWEEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWPDFNSSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTAFDGFHIHIEREENFTEYLMVDEEAHEFVAELKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	GlyTouCan ID	Source
75	N-linked (GlcNAc...) asparagine		UniProt GlyGen
154	N-linked (GlcNAc...) asparagine	G62765YT G28541PG G31852PQ G41247ZX	UniProt GlyGen
156		G49108TO	The O-GlcNAc Database
189	N-linked (GlcNAc...) asparagine		UniProt GlyGen
201	N-linked (GlcNAc...) asparagine		UniProt GlyGen
227	N-linked (GlcNAc...) asparagine	G62765YT	UniProt GlyGen
278	N-linked (GlcNAc...) asparagine		UniProt GlyGen
287	N-linked (GlcNAc...) asparagine		UniProt GlyGen
323	N-linked (GlcNAc...) asparagine		UniProt GlyGen
324	N-linked (GlcNAc...) asparagine		UniProt GlyGen