Neprilysin-1

Summary
UniProt ID
Q18673
Gene Symbol
  • nep-1
Organism
Caenorhabditis elegans
External Links
GlycoProtDB
GPDB0000647
Annotation
Keyword
  • Disulfide bond
  • Glycoprotein
  • Metal-binding
  • Metalloprotease
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
  • Zinc
Gene Ontology (GO)
Displaying 1 entry
GO Term
protein processing
Displaying 1 entry
GO Term
plasma membrane
Displaying all 2 entries
GO Term
metalloendopeptidase activity
metal ion binding
Sequence
MYTRFGPPIVFLISCYALILCGTVDALPRAPYFNDDINKTTTTSEDKTVGNTVVEEEKKTYTVGDSEGYQEASRLLQKSLNLSLDPCDDFFEYACRAWVDSHPIPDDLTSYSQFTATREKVLAEMRKLYEDNTSIPTSKSIALIKQIYNTCMDTEKHNAVGARDLLEKIKTYGYWPMVHNEKWRESTFDLTKLLSNTIQSRDVSVFFDFGPAEDSRNVSRRLLSFDQGSLGLGYSTRDYYLDEKKYEKQMKAYRKYTIGKVRYYTEDAGMAVNESKIESDVDEIIAFEKEWAQILVAEEDRRNYTKLYNVRRFDDLKEYMSIIDWKKLTLSTTPFLVHSYLKTNPSIIISDVEYLQKMNTLLQNTDPRIVTNYILLRWAGSWSQEIGKKYEDLQQEFAFQMYGRKQRQPRWKDCVSSAGGKLSYASGSMYVRKYFDANAKNTTLDMITDLQEAFRNMMHANDWMDAETKKYALEKADQMLKQIGYPDFILNDEKLDDWYKGLEGAPEDSFSQLVEKSIQWRNNFYYRRLLEPVNRFEFISSAAVVNAFYSPTRNAIAFPAGILQQPFFDARFPKALNYGGIGAVIGHEITHGFDDTGRQFDNVGNLRDWWDNTTSSKFNERTQCIIEQYADVKLRGTDLRINGKLTQGENIADNGGIKQAFKAYKSYLEKHGGQEARLPQFESLTNEQLFFVGYAQVWCGAKTPETKTLLLLTDPHSPETARVNTVLTNQPEFAEAFKCPAGSPMNPTKRCVVW
Glycosylation Sites
Displaying all 8 entries
Position Description PubMed ID GlyTouCan ID Source
38 N-linked (GlcNAc...) asparagine
81 N-linked (GlcNAc...) asparagine
132 N-linked (GlcNAc...) asparagine
217 N-linked (GlcNAc...) asparagine
273 N-linked (GlcNAc...) asparagine
303 N-linked (GlcNAc...) asparagine
441 N-linked (GlcNAc...) asparagine
612 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Metabolism of Angiotensinogen to Angiotensins Caenorhabditis elegans
Neutrophil degranulation Caenorhabditis elegans
Physiological factors Caenorhabditis elegans

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024