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Heat shock protein 90

Summary

UniProt ID

Q18688

Gene Symbol

daf-21

Organism

Caenorhabditis elegans

External Links

PubChem: Q18688
The O-GlcNAc Database: Q18688

Annotation

Keyword

3D-structure
ATP-binding
Cell cycle
Chaperone
Cytoplasm
Direct protein sequencing
Reference proteome
Stress response

Gene Ontology (GO)

Displaying entries **1 - 10** of 16 in total

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GO Term
protein dephosphorylation
defense response to Gram-negative bacterium
protein folding
protein export from nucleus
determination of adult lifespan
response to heat
positive regulation of phosphoprotein phosphatase activity
dauer larval development
chemotaxis
cell cycle

Displaying **all 9** entries
GO Term
protein-containing complex
HSP90-CDC37 chaperone complex
cytosol
membrane raft
protein serine/threonine phosphatase complex
protein folding chaperone complex
perinuclear region of cytoplasm
cytoplasm
plasma membrane

Displaying **all 8** entries
GO Term
protein phosphatase 5 binding
nuclear glucocorticoid receptor binding
identical protein binding
unfolded protein binding
ATP hydrolysis activity
ATP binding
disordered domain specific binding
ATP-dependent protein folding chaperone

Annotation information from UniProt.

Sequence

MSENAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKEDQIDFLEERKIKEIVKKHSQFIGYPIKLVVEKEREKEVEDEEAVEAKDEEKKEGEVENVADDADKKKTKKIKEKYFEDEELNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFENKKSKNSIKLYVRRVFIMENCEELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCMELIDEVAEDKDNFKKFYEQFGKNLKLGIHEDSTNRKKLSDFLRYSTSAGDEPTSLKEYVSRMKENQTQIYYITGESKDVVAASAFVERVKSRGFEVLYMCDPIDEYCVQQLKEYDGKKLVSVTKEGLELPETEEEKKKFEEDKVAYENLCKVIKDILEKKVEKVGVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHAIMKTLRDRVEVDKNDKTVKDLVVLLFETALLASGFSLEEPQSHASRIYRMIKLGLDIGDDEIEDSAVPSSCTAEAKIEGAEEDASRMEEVD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 12 in total

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Pathway Name	Organism
Aryl hydrocarbon receptor signalling	Caenorhabditis elegans
Downregulation of ERBB2 signaling	Caenorhabditis elegans
Drug-mediated inhibition of ERBB2 signaling	Caenorhabditis elegans
Extra-nuclear estrogen signaling	Caenorhabditis elegans
HSF1 activation	Caenorhabditis elegans
HSF1-dependent transactivation	Caenorhabditis elegans
HSP90 chaperone cycle for SHRs	Caenorhabditis elegans
Neutrophil degranulation	Caenorhabditis elegans
Signaling by ERBB2	Caenorhabditis elegans
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	Caenorhabditis elegans

GlyTouCan

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UniCarb-DR

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International Collaboration

Acknowledgements