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Standards Ontologies Notations
Neprilysin-21

Summary
UniProt ID
Q22523
Gene Symbol
  • nep-21
Organism
Caenorhabditis elegans
External Links
GlycoProtDB
GPDB0000789
Annotation
Keyword
  • Cell membrane
  • Disulfide bond
  • Glycoprotein
  • Metal-binding
  • Metalloprotease
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
  • Zinc
Gene Ontology (GO)
Displaying 1 entry
GO Term
protein processing
Displaying 1 entry
GO Term
plasma membrane
Displaying all 2 entries
GO Term
metal ion binding
metalloendopeptidase activity
Annotation information from UniProt.
Sequence
MKPENGAATWHPAKRSCLGRLTTLETLLLVFLGLLITALLSVLFLWLWVLDGYKTFTDGRPIYPLPFENSSVAVDRSAKNHNDVVCTSRECVRLAGFLAENLNSKINPCEDFYEFACGNYGLNKNLPANKPLRHTISDVQSRLNKQVKSMLQSPISANEKPWDKVAKGYYQKCLDEEELESTGVEAMRDIAKRIGGWPTLEGDKWQEWSHSWEEQIALVLNLTGVNAVILEMAVTHDPSNSSRSVIELDQPKWGAGSRYPYLSGANDPMLRNYTTLMKMTAVALGADPAIAEKEMNEAMEFELKLVNFSADDMVRRDPERGNNRFELWQLKSVFPFINFEKYLKTVFKELVALSPNHTVIVREIDYFVGIQHVLQSTPKRVLANYISWRLVQGFSPFLPPSAREPFYQFKANQTGMFNSPPPDRWEDCVTLSVIMMDMPVGRLFVENFFEKERAMKKMTELTSYLKNEFIKQLHVLDWMDEITRRRAISKANMIEYKSGFPMVLFNDTWMEKNWGMIIKPREYLLHLTIRVKLVRFTEELLRLDQPLDRSMWFQSPAQVDAYYAPNNNEMIFPAGIMQFPFLTLGVPNYITYGMVGAVIGHEVSHAFDDQGGQYDEMGNLNDWWDAETEEKFIEKTRCFVRQYENVHVVEADIHLNGQLSLGENIADNGGVKTAFNAYKAWKSNTTGISEPALPGFQNFTSQQMFFLAYANNWCSLVRPKHYIQIILTDVHAPSKYRAMIPLQNRPEFAKAFQCPIGSPMNPERKCQVW
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 10 entries
Position Description PubMed ID GlyTouCan ID Source
69 N-linked (GlcNAc...) asparagine
221 N-linked (GlcNAc...) asparagine
240 N-linked (GlcNAc...) asparagine
272 N-linked (GlcNAc...) asparagine
307 N-linked (GlcNAc...) asparagine
356 N-linked (GlcNAc...) asparagine
412 N-linked (GlcNAc...) asparagine
506 N-linked (GlcNAc...) asparagine
684 N-linked (GlcNAc...) asparagine
698 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Metabolism of Angiotensinogen to Angiotensins Caenorhabditis elegans
Neutrophil degranulation Caenorhabditis elegans
Physiological factors Caenorhabditis elegans
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024