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Semaphorin-2A
Summary
- UniProt ID
- Q24323
- Gene Symbol
-
- CG4700
- Sema-2a
- Sema2a
- Gene ID
- 36846
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Developmental protein
- Differentiation
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Neurogenesis
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| endomembrane system |
| cytosol |
| GO Term |
|---|
| dendrite guidance |
| synaptic target inhibition |
| visual behavior |
| negative chemotaxis |
| semaphorin-plexin signaling pathway |
| olfactory bulb axon guidance |
| flight behavior |
| positive regulation of cell migration |
| drinking behavior |
| axon guidance |
| GO Term |
|---|
| semaphorin receptor binding |
| chemorepellent activity |
Sequence
MSLLQLSPLLALLLLLCSSVSETAADYENTWNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFDCKNHVRVIQSMDQGDRLYVCGTNAHNPKDYVIYANLTHLPRSEYVIGVGLGIAKCPYDPLDNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFDIGEYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGGKNLLAHNWATYLKARLNCSISGEFPFYFNEIQSVYQLPSDKSRFFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVLNSRVPEPRPGTCVNDTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIVQYYRNGESLSKLLDIFEVAPNEAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFRCVRDPYCGWDKEANTCRPYELDLLQDVANETSDICDSSVLKKKIVVTYGQSVHLGCFVKIPEVLKNEQVTWYHHSKDKGRYEIRYSPTKYIETTERGLVVVSVNEADGGRYDCHLGGSLLCSYNITVDAHRCTPPNKSNDYQKIYSDWCHEFEKYKTAMKSWEKKQAQCSTRQNFSSNQHPNEIFRKPNV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 95 | N-linked (GlcNAc...) asparagine |
|
||
| 163 | N-linked (GlcNAc...) asparagine |
|
||
| 190 | N-linked (GlcNAc...) asparagine |
|
||
| 229 | N-linked (GlcNAc...) asparagine |
|
||
| 314 | N-linked (GlcNAc...) asparagine |
|
||
| 401 | N-linked (GlcNAc...) asparagine |
|
||
| 563 | N-linked (GlcNAc...) asparagine |
|
||
| 658 | N-linked (GlcNAc...) asparagine |
|
||
| 670 | N-linked (GlcNAc...) asparagine |
|
||
| 708 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CRMPs in Sema3A signaling | Drosophila melanogaster |
| Other semaphorin interactions | Drosophila melanogaster |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | Drosophila melanogaster |
| Sema3A PAK dependent Axon repulsion | Drosophila melanogaster |
| Sema4D induced cell migration and growth-cone collapse | Drosophila melanogaster |
