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Complement factor H

Summary

UniProt ID: Q28085
Gene Symbol: CFH HF1
Gene ID: 280816
Organism: Bos taurus (domestic cattle)

External Links

Re-Glyco: Q28085

Annotation

Keyword: 3D-structure Complement alternate pathway Direct protein sequencing Disulfide bond Glycoprotein Reference proteome Repeat Secreted Signal Sulfation Sushi

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	Reference
complement activation	IBA	GO_REF
complement activation, alternative pathway

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

complement activation

complement activation, alternative pathway

activation of immune response [inference]

complement activation

complement activation, alternative pathway

immune response [inference]

humoral immune response [inference]

complement activation

complement activation, alternative pathway

innate immune response [inference]

complement activation, alternative pathway

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

complement activation, alternative pathway

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

complement activation, alternative pathway

immune response [inference]

humoral immune response [inference]

complement activation

complement activation, alternative pathway

innate immune response [inference]

complement activation, alternative pathway

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

complement activation, alternative pathway

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

complement activation, alternative pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

complement activation, alternative pathway

regulation of immune response [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

complement activation, alternative pathway

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

complement activation, alternative pathway

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

complement activation, alternative pathway

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

complement activation, alternative pathway

regulation of immune response [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

complement activation, alternative pathway

Displaying 1 entry
GO Term	Evidence Code	Reference
obsolete extracellular space

GO Hierarchy

cellular component

Displaying 1 entry
GO Term	Evidence Code	Reference
complement component C3b binding	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

opsonin binding [inference]

complement component C3b binding

complement binding [inference]

complement component C3b binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRFPAKIVWLVLWTVCVAEDCKEPPPRKETEILSGSWTEQTYQEGTQATYKCRPGYRTLGSIVMMCRGGKWVSLHPSRICRKKPCAHPGDTPFGSFHLAEGTQFEYGAKVVYTCDEGYQMVGEMNFRECDTNGWTNDIPICEVVKCLPVTEPENGKIFSDALEPDQEYTYGQVVQFECNSGYMLDGPKQIHCSAGGVWSAETPKCVEIFCKTPVILNGQAVLPKATYKANERVQYRCAAGFEYGQRGDTICTKSGWTPAPTCIEITCDPPRIPNGVYRPELSKYRGQDKITYECKKGFFPEIRGTDATCTRDGWVPVPRCAWKPCSYPVIKHGRLYYSYRGYFPARVNQQFVYSCDHHFVPPSQRSWDHLTCTAEGWSPEEPCLRQCIFNYLENGHTPYREEKYLQGETVRVRCYEGYSLQNDQNTMTCTESGWSPPPRCIRVKTCSKSNIRIENGFLSESTFTYPLNKQTEYKCKPGYVTADGKTSGLITCLKNGWSAQPVCIKSCDRPVFEKARVKSDGTWFRLNDRLDYECVDGYENRDGRTTGSIVCGQDGWSDKAACYERECSIPEMDPYLNAYPRKETYKVGDVLKFSCSQGRIMVGADSVQCYHFGWSPKLPTCKVKKVKSCALPPELPNGKRKEIHKEEYAHNEVVEYACNPRFLMKGSHKIQCVDGEWTALPVCIEEERTCGNIPDLDHGDVKPSVPPYHHGDSVEFSCREAFTMIGPRFITCISGEWTQPPQCIATDELRKCKGSTLFPPEGRQAHKIEYDHNTNKSYQCRGKSEHKHSICINGEWDPKVDCNEEAKIQLCPPPPQVPNACDMTTTVNYQDGEKISILCKENYLIQDAEEIVCKDGRWQSIPRCIEKIGCSQPPQIDHGTISSSSSAEERREIHEQRLYAHGTKLSYTCEEGFEISENNVIICHMGKWSSPPQCVGLPCGLPPYVQNGVVSHKKDRYQYGEEVTYDCDEGFGTDGPASIRCLGGEWSRPQDCISTNCVNLPTFEDAVLTDREKDFYRSGEQVAFKCLSYYQLDGSNTIQCIKSKWIGRPACRDVSCGNPPQVENAIIHNQKSKYQSEERARYECIGNYDLFGEMEVVCLNGTWTEPPQCKDSQGKCGPPPPIDNGDITSLLQSVYPPGMIVEYRCQAYYELRGNKNVVCRNGEWSQLPKCLEACVISEETMRKHHIQLRWKHDKKIYSKTEDTIEFMCQHGYRQLTPKHTFRATCREGKVVYPRCG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites