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Guanylate cyclase

Summary

UniProt ID

Q2TAY4

Gene Symbol

Npr1

Gene ID

18160

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0004072
Re-Glyco: Q2TAY4

Annotation

Keyword

Chloride
Coiled coil
Disulfide bond
GTP-binding
Glycoprotein
Lyase
Phosphoprotein
Receptor
Signal
Transmembrane helix
Vasoactive
cGMP biosynthesis

Gene Ontology (GO)

Displaying **all 2** entries
GO Term
membrane
ANPR-A receptor complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 6** entries
GO Term
positive regulation of cGMP-mediated signaling
receptor guanylyl cyclase signaling pathway
negative regulation of smooth muscle cell proliferation
protein phosphorylation
cGMP-mediated signaling
dopamine metabolic process

Displaying **all 5** entries
GO Term
natriuretic peptide receptor activity
guanylate cyclase activity
protein kinase activity
ATP binding
peptide hormone binding

Annotation information from UniProt.

Sequence

MPGSRRVRPRLRALLLLPPLLLLRSGHASDLTVAVVLPLTNTSYPWSWARVGPAVELALGRVKARPDLLPGWTVRMVLGSSENAAGVCSDTAAPLAAVDLKWEHSPAVFLGPGCVYSAAPVGRFTAHWRVPLLTAGAPALGIGVKDEYALTTRTGPSHVKLGDFVTALHRRLGWEHQALVLYADRLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGDPDHYTKLLRTVQRKGRVIYICSSPDAFRNLMLLALDAGLTGEDYVFFHLDVFGQSLQGAQGPVPRKPWERDDGQDRRARQAFQAAKIITYKEPDNPEYLEFLKQLKLLADKKFNFTMEDGLKNIIPASFHDGLLLYVQAVTETLAQGGTVTDGENITQRMWNRSFQGVTGYLKIDRNGDRDTDFSLWDMDPETGAFRVVLNFNGTSQELMAVSEHRLYWPLGYPPPDIPKCGFDNEDPACNQDHFSTLEVLALVGSLSLVSFLIVSFFIYRKMQLEKELVSELWRVRWEDLQPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAIGSHGNLKSSNCVVDGRFVLKITDYGLESFRDPEPEQGHTLFAKKLWTAPELLRMASPPARGSQAGDVYSFGIILQEIALRSGVFYVEGLDLSPKEIIERVTRGEQPPFRPSMDLQSHLEELGQLMQRCWAEDPQERPPFQQIRLALRKFNKENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGQLHAREVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALRIHLSSETKAVLEEFDGFELELRGDVEMKGKGKVRTYWLLGERGCSTRG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites