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Sterol regulatory element-binding protein 2

Summary

UniProt ID

Q3U1N2

Gene Symbol

Srebf2
Srebp2

Gene ID

20788

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q3U1N2
PubChem: Q3U1N2
The O-GlcNAc Database: Q3U1N2
O-GlcNAcAtlas: Q3U1N2
Re-Glyco: Q3U1N2

Annotation

Keyword

Activator
Alternative splicing
Cholesterol metabolism
Cytoplasmic vesicle
DNA-binding
Endoplasmic reticulum
Golgi apparatus
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
nucleus
cytoplasm
membrane
Golgi membrane
nucleoplasm
ER to Golgi transport vesicle membrane
SREBP-SCAP-Insig complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 12 in total

1

2

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GO Term
regulation of DNA-templated transcription
regulation of Notch signaling pathway
positive regulation of transcription by RNA polymerase II
cholesterol metabolic process
cellular response to starvation
cholesterol homeostasis
positive regulation of miRNA transcription
positive regulation of cholesterol storage
SREBP signaling pathway
positive regulation of cholesterol biosynthetic process

Displaying **all 7** entries
GO Term
DNA binding
DNA-binding transcription factor activity
sequence-specific DNA binding
protein dimerization activity
transcription cis-regulatory region binding
DNA-binding transcription repressor activity, RNA polymerase II-specific
E-box binding

Annotation information from UniProt.

Sequence

MDESSELGVLETMETLTELGDELTLGDIDEMLQFVSNQVGEFPDLFSEQLCSSFPGGGSNGGSGNNSSGRGNNGGATDPAVQRSFSQVPLSTFSPSAASPQAPALQVKVSPTPPRATPVLQPRPQPQPQPPAQLQQQTVMITPTFSTAPQTRIIQQPLIYQNAATSFQVLQPQVQSLVTSPQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVAAPQVQQVPVLVQPQIIKTDSLVLTTLKTDGSPVMAAVQNPALTALTAPIQTAALQVPTLVGSNGTILTTMPVMMGQEKVPIKQVPGGVKQLDPPKEGERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKSGVLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSLVDSDVDLKIDDFNQNVLLMSPPASDSGSQAGFSPYSIDSEPGSPLLDDAKVKDEPDSPPVALGMVDRSRILLCVLTFLGLSFNPLTSLLQWGGAHNTDQHPYSGSGRSVLSLESGAGGWFDWMVPTLLLWLVNGVIVLSVFVKLLVHGEPVIRPHSRPSVTFWRHRKQADLDLAKGDFAAAAANLQTCLSVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQRWRATPATAAGFEDEAKSSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKILPSTLIEIHLTAAMGLKTRCGGKLGFLASYFLNRAQSLCGPEHSTVPDSLRWLCHPLGQKFFMERSWSIKSAAKESLYCAQRSPADPIAQVHQAFCKNLLERAVESLVKPQAKKKAGDQEEESCEFSSALEYLKLLHSFVDSVGFVTSPFSSSSVLRSALGPDVICRWWTSAVTMAISWLQGDDAAVRSRFTEVERVPKALEVTESPLVKAVFYTCRAMHASLSGKADGQQNSFCHCERASGHLWSSLNVSGTTSDPSLNHVIQLFTCDLLLSLRTALWQKQASASQLLGETYHASGTELAGFQRDLGSLRRLAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRPTQNTKHGEVDTWPGQRERATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCSDCQQMIVKLGGGTAIAAS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites